ArticleFrontiers in surgery2026
Enhanced parathyroid identification and preservation in total thyroidectomy using combined near-infrared autofluorescence and carbon nanoparticles.
Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Postoperative hypoparathyroidism remains a common complication after total thyroidectomy. This study aimed to assess whether combining near-infrared autofluorescence (NIRAF) imaging with carbon nanoparticle suspension (CN) improves parathyroid gland (PG) identification and functional preservation in patients undergoing total thyroidectomy for papillary thyroid carcinoma (PTC). Methods: A total of 80 patients with PTC undergoing total thyroidectomy with central neck dissection (CND) were randomly divided into two groups. The CN group ( Results: The NIRAF + CN group identified significantly more PGs than the CN group (147/160 [91.9%] vs. 135/160 [84.4%], Conclusions: The combined use of NIRAF and CN enhances intraoperative PG preservation and improves early parathyroid function.
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