ArticleHealth science reports2026
Clinical Significance of Tumor Invasion Gene Profiling in Early-Stage Hormone Receptor-Positive Breast Cancer: A Cross-Sectional Study.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and Aims: Advanced breast cancer is a leading cause of cancer-associated death in women. It is critical to find biomarkers to identify patients who are more prone to progress to advanced disease and would be better served with more aggressive treatments. Hormone receptor-positive breast cancers make up about 70% of all breast cancers. The analysis of gene amplification and expression has been utilized to classify breast tumors into medically useful risk groups. In the present study, we selected five genes ( Methods: Two hundred and thirty-nine early-stage hormone receptor-positive breast cancer patients were analyzed. Patients were required to have FFPE (formalin-fixed paraffin-embedded) samples from the primary tumor. Expression of the selected genes was determined using TaqMan expression assays. Results: Expression of Conclusion: We found a significant association between
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