ArticleFrontiers in immunology2026
Intragraft donor-specific antibodies reflect histologic heterogeneity in kidney allografts with concurrent serum DSA.
Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Circulating donor-specific antibodies (sDSA) are clinically important markers of alloimmune risk, but their presence or strength does not always correspond to concurrent antibody-mediated rejection (ABMR) in kidney transplantation. We investigated whether intragraft donor-specific antibodies (gDSA) detected in kidney biopsy eluates are associated with histologic findings in recipients with concurrent sDSA positivity. Methods: All available frozen kidney biopsies in recipients with concurrent weak to moderate sDSA at Seoul National University Hospital between January 2020 and June 2024 were included. Sixty biopsy eluates from 60 patients were tested using a Luminex single antigen bead assay and analyzed according to biopsy findings. Results: The prevalence of gDSA differed significantly across histologic diagnoses (overall Conclusions: In kidney transplant recipients with concurrent sDSA, the presence and intensity of gDSA varied according to biopsy-proven histologic findings, most prominently in aABMR and related lesions. These findings suggest that gDSA may provide additional tissue-level immunologic context for understanding histologic heterogeneity among kidney transplant recipients with circulating sDSA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.