ArticleACS applied nano materials2026
Influence of Ligand Functionalization on the Synthesis of Metallic-Decorated Magnetic Nanoparticles for Antibacterial Treatment.
Article in ACS applied nano materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The inherent magnetism of iron oxide nanoparticles (IONPs) provides appealing benefits for antibacterial treatment, as IONPs can be readily guided, concentrated, and removed from a specific site. Additionally, gold and silver demonstrate antibacterial properties that effectively inhibit bacterial growth. By combining one of these antibacterial metals and the IONP, a dual-purpose metallic nanoparticle treatment can thus be constructed. In our study, we developed silica-coated IONPs to facilitate the binding and decoration with either gold (Au) or silver (Ag). Therefore, the focus of this research is to apply the hard/soft acid/base (HSAB) theory by investigating the affinity of Au or Ag after encapsulating the IONPs with one of three silane capping agents, providing either an amine (AP-SIONP), hydroxide (T-SIONP), or thiol (MP-SIONP). With the use of inductively coupled plasma optical emission spectroscopy (ICP-OES), the amount of metal decorated on the antibacterial metallic SIONPs was compared. We demonstrated that although both Au and Ag had an affinity for all three ligands, Au (79 ± 18 and 23 ± 0 μg/L) and Ag (72 ± 36 and 160 ± 23 μg/L) had a higher affinity for amines and thiols, respectively. Finally, the optimal Au and Ag SIONPs were applied to a Gram-negative (
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