Evidence map›Paper›PMID 42415879›Full record

ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

Comparison of Effects of Postextubation Noninvasive Ventilation with Passive Humidification and High-flow Nasal Cannula in Patients with High Risk of Extubation Failure: A Randomized Comparative Study.

Nimisha S Patil, Madhulika Dubey, Mohd Mustahsin, Krishna P Mall, Supriya Singh

Abstract read
In one paragraph

Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. High-flow Nasal Cannula Over Non-invasive Ventilation in Preventing Reintubation: Signal Bias or Both?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
  2. What Explains the Reported Benefit of High-flow Nasal Cannula in High-risk Extubated Patients?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
  3. High-flow Nasal Cannula Oxygen vs Non-invasive Ventilation with Passive Humidification: Are We Comparing Like with Like?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nimisha S PatilDepartment of Anaesthesiology, Era's Lucknow Medical College and Hospital, Lucknow, Uttar Pradesh, India.ORCID https://orcid.org/0009-0001-0541-1285
Madhulika DubeyDepartment of Critical Care Medicine, Kalyan Singh Super Specialty Cancer Institute, Lucknow, Uttar Pradesh, India.ORCID https://orcid.org/0000-0002-0329-1056
Mohd MustahsinDepartment of Critical Care Medicine, Era's Lucknow Medical College and Hospital, Lucknow, Uttar Pradesh, India.ORCID https://orcid.org/0000-0003-2503-1906
Krishna P MallDepartment of Anaesthesiology, Era's Lucknow Medical College and Hospital, Lucknow, Uttar Pradesh, India.ORCID https://orcid.org/0000-0002-5840-621X
Supriya SinghDepartment of Anaesthesiology, Sarojini Naidu Medical College, Agra, Uttar Pradesh, India.ORCID https://orcid.org/0000-0003-0044-3365

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Weaning patients with a high risk of extubation failure off the ventilator can be challenging and associated with complications. High-flow nasal cannula (HFNC) and noninvasive ventilation (NIV) have been used after extubation in various settings. This study suggests the better modality between HFNC and NIV to prevent reintubation in these patients. Patients and methods: A single-centered, prospective, randomized comparative study was conducted in the adult medical intensive care unit (ICU) of our center. A total of 150 critically ill patients with a high risk of extubation failure were randomized in a 1:1 ratio to receive either HFNC or NIV immediately after extubation for 48 hours. The rate of reintubation within 48 hours of extubation was compared between the groups. Results: The rate of reintubation within 48 hours was lower in the HFNC group than the NIV group ( Conclusion: High-flow nasal cannula performed better than NIV in preventing reintubation at 48 hours in patients with a high risk of extubation failure. How to cite this article: Patil NS, Dubey M, Mustahsin M, Mall KP, Singh S. Comparison of Effects of Postextubation Noninvasive Ventilation with Passive Humidification and High-flow Nasal Cannula in Patients with High Risk of Extubation Failure: A Randomized Comparative Study. Indian J Crit Care Med 2026;30(5):371-378.

Indexed as

Critically ill patientsHigh-flow nasal cannulaHigh risk of extubation failureNoninvasive ventilationReintubation

Identifiers

PMID42415879
PMCPMC13337616

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.