Evidence map›Paper›PMID 42415865›Full record

ArticleFrontiers in oncology2026

Adjunctive photodynamic therapy improves outcomes and quality of life in condyloma acuminatum after radical cervical cancer surgery.

Cheng Zhang, Wei Zheng, Xiuli Wang, Zihan Wang

Abstract read
In one paragraph

Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cheng Zhang *Gynecology Department, Yantai Yuhuangding Hospital, Yantai, China.
Wei Zheng *Gynecology Department, Yantai Yuhuangding Hospital, Yantai, China.
Xiuli WangGynecology Department, Yantai Yuhuangding Hospital, Yantai, China.
Zihan WangDermatology Department, Yantai Mountain Hospital, Yantai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Condyloma acuminatum (CA), caused by human papillomavirus infection, frequently persists or recurs in patients undergoing treatment for cervical cancer and can significantly impair postoperative quality of life. Purpose: This study aimed to compare the efficacy of photodynamic therapy (PDT) combined with CO Methods: In this retrospective study, 148 patients were divided into a single laser group (n=81) receiving only CO Results: The combined PDT group demonstrated a significantly higher overall symptom relief rate (94.03% vs. 77.78%, P = 0.006) and lower recurrence rates at 3 months (7.46% vs. 24.69%) and 6 months (11.94% vs. 34.57%) compared to the single laser group. Greater improvements were observed in DLQI (10.46 vs. 11.73, P = 0.001), FSFI scores (25.09 vs. 23.83, P = 0.013), and across multiple EORTC QLQ-C30 domains-including physical, role, emotional, and social functioning, as well as global health status (all P<0.05) in the combined group. Viral load reduction was more pronounced (0.97 vs. 2.44 ×10 Conclusion: The addition of photodynamic therapy, a light-based immunomodulatory approach within photomedicine, enhances clinical outcomes and supports improved quality of life, potentially through synergistic cytotoxic and immune-mediated mechanisms.

Indexed as

cervical cancerCO2 lasercondyloma acuminatumphotodynamic therapyquality of life

Identifiers

PMID42415865
PMCPMC13337641

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.