Evidence map›Paper›PMID 42415820›Full record

ArticleOpen life sciences2026

Hysteroscopic observation of the association between endometrial polyps and endometriosis: a retrospective cohort study.

Hui Liu, Lianhua Tang

Abstract read
In one paragraph

Article in Open life sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hui LiuObstetrics and Gynecology, Guangzhou Twelfth People's Hospital, Guangzhou City, Guangdong Province, 510620, China.
Lianhua TangGynecology, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou City, Guangdong Province, 510440, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This single-centre retrospective study (100 women with endometrial polyps, mean age 41.8 ± 8.2 years) investigated the association between endometrial polyps and endometriosis. Endometriosis was confirmed in 13 % of patients. Multiple polyps were significantly more common in the endometriosis group (69.2 % vs. 42.5 %, P = 0.046). Women with endometriosis had higher CA125 levels (89.3 ± 45.2 vs. 18.6 ± 12.3 U/mL, P < 0.001) and higher rates of dysmenorrhoea (100 % vs. 35.6 %, P < 0.001). Independent predictors of endometriosis were dysmenorrhoea (aOR[95 % CI] = 8.45 [2.34-30.52], P = 0.001), CA125 > 35 U/mL (aOR[95 % CI] = 12.67 [3.82-42.01], P < 0.001), and multiple polyps (aOR[95 % CI] = 3.12 [1.08-9.01,], P = 0.036). CA125 > 35 U/mL showed an area under the curve (AUC) of 0.852 (95 % CI: 0.778-0.926), and the combined model achieved an AUC of 0.938 (95 % CI: 0.885-0.991) with a bootstrap-corrected AUC of 0.925. During a median follow-up of 17.5 months, polyp recurrence was significantly higher in women with EM (45.5 % vs. 17.6 %, P = 0.047). These findings demonstrate that the combination of multiple polyps, dysmenorrhoea, and elevated CA125 levels should raise suspicion for concurrent EM in women with EPs, suggesting potential shared pathophysiological mechanisms with important implications for clinical management, surgical planning, and fertility counselling.

Indexed as

CA-125 antigendysmenorrhoeaendometriosishysteroscopyinfertility

Identifiers

PMID42415820
PMCPMC13340640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.