SynthesisFrontiers in medicine2026
Evaluation of
Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Understanding the role of genetic polymorphisms in cluster of differentiation (CD)-related genes is crucial for elucidating susceptibility to immune thrombocytopenia (ITP). This study evaluates the polymorphisms of Methods: A comprehensive literature review was conducted by a single investigator across multiple databases, including PubMed/Medline, Web of Science, Scopus, and Cochrane Library, up to 7 December 2025. The effect sizes were calculated using Review Manager 5.3 and presented as odds ratios (OR) with a 95% confidence interval. Analyses for publication bias, meta-regression, and sensitivity were performed using Comprehensive Meta-Analysis version 3.0. Results: Thirty-three articles were included in both qualitative and quantitative syntheses. Significant associations were found for the FcγRIIIA-158 F/V polymorphism across all genetic models, with the highest pooled OR of 2.61 in the homozygous model. No significant associations were observed for the Conclusion: The
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.