ArticleFrontiers in medicine2026
Intraoperative allogeneic blood transfusion is not associated with postoperative acute kidney injury and in-hospital mortality in liver transplantation patients: a propensity score matching analysis.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Many studies have found a correlation between perioperative blood transfusion and postoperative complications and mortality in liver transplant (LT) patients. The purpose of our study is to identify independent risk factors for intraoperative blood transfusion in liver transplant patients and to explore the effect of intraoperative blood transfusion on postoperative acute kidney injury (AKI) and in-hospital mortality in LT patients. Methods: A total of 686 liver transplant patients were included in the study, of which 517 (75.4%) patients received an intraoperative blood transfusion (IBT group). Univariable and multivariable regression were used to identify independent risk factors for IBT, and propensity score matching (PSM) and multivariable regression analysis were used to analyze the effect of IBT on postoperative AKI and in-hospital mortality. Results: The multivariable regression analysis revealed that sex ( Conclusion: In our matched cohort, the vast majority of patients, received no more than 8 units of blood. Intraoperative allogeneic blood transfusion does not influence postoperative acute kidney injury and in-hospital mortality in liver transplantation patients. Multicenter, prospective studies are needed in the future to validate our findings. Clinical trial registration: CHiCTR1900024561; https://www.chictr.org.cn/showproj.html?proj=41126.
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