Evidence map›Paper›PMID 42415743›Full record

ArticleCurrent opinion in endocrine and metabolic research2024

The role of primary cilia in the testis.

Nathalia de Lima E Martins Lara, Anja Elsenhans, Rkia Dardari, Ina Dobrinski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current opinion in endocrine and metabolic research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nathalia de Lima E Martins LaraDepartment of Biochemistry and Molecular Biology, Cumming School of Medicine, And Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, T2N 1N4, Canada.
Anja ElsenhansDepartment of Biochemistry and Molecular Biology, Cumming School of Medicine, And Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, T2N 1N4, Canada.
Rkia DardariDepartment of Biochemistry and Molecular Biology, Cumming School of Medicine, And Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, T2N 1N4, Canada.
Ina DobrinskiDepartment of Biochemistry and Molecular Biology, Cumming School of Medicine, And Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, T2N 1N4, Canada.

Funding

Transplantation of Testis Stem Cells in Large AnimalsR01OD016575 · OD · UNIVERSITY OF CALGARY · PI DOBRINSKI, INA · 2013 to 2024
$2.4M
NIH HHS R01 OD016575
6 · The paper itself

Abstract

A better understanding of the role primary cilia play in the testis is becoming increasingly important in the context of male reproductive health since defects in cilia have been associated with male infertility and reproductive disorders. Primary cilia are found on most somatic cell types within the testis, including Sertoli cells, peritubular myoid cells, and Leydig cells, especially during embryonic and neonatal stages. Primary cilia are involved in signaling pathways that are important for differentiation and function of testicular somatic cells, and cilia are also implicated in testicular morphogenesis. These observations indicate that testicular primary cilia play an integral role in regulating testis development and function.

Indexed as

Male fertilityPrimary ciliaSpermatogenesisTesticular developmentTesticular morphogenesisTestis

Identifiers

PMID42415743
PMCPMC13340577

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.