ArticleEJHaem2026
Effectiveness and Safety of Prophylactic Low-Dose Emicizumab in Young Children With Hemophilia A: A Multicenter Retrospective Study.
Article in EJHaem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Real-world data on low-dose emicizumab in young children with hemophilia A are limited. Methods: This multicenter retrospective study included 26 children (median age: 2.2 years) receiving individualized low-dose emicizumab (2019-2025). Results: Over 48 months, the annualized bleeding rate decreased from 5.31 to 0.60 ( Conclusions: Low-dose emicizumab effectively reduces bleeding and improves quality of life, supporting its feasibility in resource-limited settings. Trial Registration: The authors have confirmed clinical trial registration is not needed for this submission.
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