Trial reportJournal of rehabilitation medicine2026
The impact of persistent post-concussion symptoms and exercise intolerance on patient-specific functioning after mild traumatic brain injury: a biopsychosocial perspective.
Trial report in Journal of rehabilitation medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore activity limitations in a biopsychosocial context in a randomized controlled trial studying sub-symptom threshold aerobic exercise after mild traumatic brain injury.
designQualitative and quantitative approaches. PATIENTS: Eighty-one participants (58% female; median age 32.3) with persistent post-concussion symptoms and exercise intolerance.
methodsActivity limitations assessed with the Patient Specific Functional Scale were categorized into main and subcategories using thematic analyses. Subcategories were linked to the International Classification of Functioning, Disability and Health. Group differences and changes over time were examined using linear mixed-effects models.
resultsOf 390 activities, 6 main categories and 24 subcategories were identified: physical activity and exercise (31%), work/education (16%), activities of daily living (15%), social activities (15%), cognition/energy (14%), and sensory-demanding environments (9%). Most subcategories (86%) were linked to the activity and participation domain. There were no group differences in activity limitations at 3 (p = 0.60) and 6 (p = 0.48) months. However, all patients improved from 3.3 (2.9-3.7) at baseline to 5.4 (5.0-5.9, p < 0.001) at 3 months, and 6.2 (5.8-6.7, p < 0.001) at 6 months.
conclusionLimitations in daily activities were reported across multiple domains. While no differences were found between groups, patient‑reported limitations showed significant improvement over time and may inform individualized rehabilitation strategies.
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