Evidence map›Paper›PMID 42415661›Full record

ArticleCanadian respiratory journal2026

Survival Analysis of Risk Factors for Death in Patients With TB Based on Clinical and Imaging Characteristics.

Jing Han, Peng Li, Lixia Shi, Yi Xie, Xiaolong Liu, Wanjie Yang, Zhiheng Xing

Abstract read
In one paragraph

Article in Canadian respiratory journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jing HanDepartment of Medical Affairs, Haihe Hospital, Tianjin University, Tianjin, 300350, China, tju.edu.cn.ORCID https://orcid.org/0000-0003-2360-1290
Peng LiHaihe Clinical School, Tianjin Medical University, Tianjin, 300350, China, tijmu.edu.cn.ORCID https://orcid.org/0009-0001-8485-2635
Lixia ShiTianjin Institute of Respiratory Diseases, Tianjin, 300350, China, tju.edu.cn.ORCID https://orcid.org/0000-0003-2814-9600
Yi XieTianjin Institute of Respiratory Diseases, Tianjin, 300350, China, tju.edu.cn.ORCID https://orcid.org/0000-0002-5672-3158
Xiaolong LiuTianjin Institute of Respiratory Diseases, Tianjin, 300350, China, tju.edu.cn.ORCID https://orcid.org/0009-0006-8941-1085
Wanjie YangTianjin Institute of Respiratory Diseases, Tianjin, 300350, China, tju.edu.cn.ORCID https://orcid.org/0009-0009-5592-145X
Zhiheng XingTianjin Institute of Respiratory Diseases, Tianjin, 300350, China, tju.edu.cn.ORCID https://orcid.org/0000-0003-2695-9183

Funding

Natural Science Foundation of Tianjin City 23JCQNJC01490Natural Science Foundation of Tianjin City 23JCZDJC00970Tianjin Health Research Project (to W.J.Y.) TJWJ2024ZD009Tianjin Science and Technology Major Project (to W.J.Y.) 24ZXKJGX00070
6 · The paper itself

Abstract

backgroundThis study was performed to explore the predictive factors for mortality among patients with tuberculosis undergoing directly observed treatment, short-course (DOTS) therapy and to develop a clinically applicable visualization tool for mortality risk prediction.

methodsWe conducted a retrospective cohort study of 9270 patients (8884 survivors and 386 deaths, yielding a mortality rate of 4.16%) from 2014 to 2024, utilizing data from the tuberculosis management information system in Tianjin. Cox proportional hazards regression was used to identify independent risk factors, a nomogram model was constructed, and model performance was evaluated using cross-validation and ROC curves.

resultsMale sex, advanced age, human immunodeficiency virus-positive status, pulmonary cavities, initial sputum positivity, pericardial effusion, and miliary nodules emerged as independent risk factors for DOTS mortality. The nomogram demonstrated an area under the curve of 0.81 for predictions at 2, 6, and 12 months; calibration curves revealed high concordance between predicted and actual risk (with average absolute errors of 0.001, 0.001, and 0.004, respectively); receiver operating characteristic curves confirmed robust discriminative ability of the model.

conclusionThe nomogram developed in this study successfully integrates multiple mortality predictive factors and exhibits exhibiting excellent discriminatory power and calibration performance, thereby providing quantitative decision support for early identification and personalized intervention strategies in high-risk patients with tuberculosis receiving DOTS therapy.

Indexed as

TuberculosisTuberculosis, PulmonaryAdultChinaFemaleHumansMaleMiddle AgedNomogramsProportional Hazards ModelsRetrospective StudiesRisk FactorsROC CurveSurvival AnalysisDOTSHIVnomogramtuberculosis

Identifiers

PMID42415661
PMCPMC13342835

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.