Evidence map›Paper›PMID 42415627›Full record

ArticleLupus2026

Diagnosis to dialogue: Reproductive health conversations and guideline adherence in women with lupus.

Akhil Sood, Leanna M Wise, Sadaf Sediqi, Amanda Moyer, Ellie Diamond, Alyssa Howren, Yashaar Chaichian, Julia F Simard

Abstract read
In one paragraph

Article in Lupus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Akhil SoodStanford University School of Medicine, Palo Alto, CA, USA.ORCID 0000-0001-6313-2738
Leanna M WiseUniversity of Southern California Keck School of Medicine, Los Angeles, CA, USA.
Sadaf SediqiStanford University School of Medicine, Palo Alto, CA, USA.
Amanda MoyerStanford University School of Medicine, Palo Alto, CA, USA.
Ellie DiamondStanford University School of Medicine, Palo Alto, CA, USA.
Alyssa HowrenStanford University School of Medicine, Palo Alto, CA, USA.
Yashaar ChaichianStanford University School of Medicine, Palo Alto, CA, USA.
Julia F SimardStanford University School of Medicine, Palo Alto, CA, USA.

Funding

Training Program in Adult and Pediatric RheumatologyT32AR050942 · NIAMS · STANFORD UNIVERSITY · PI LEWIS, DAVID BRAM, ROBINSON, WILLIAM H · 2005 to 2025
$6.6M
Can hydroxychloroquine prevent preeclampsia and preterm delivery in lupus pregnancy?R01AR077103 · NIAMS · STANFORD UNIVERSITY · PI SIMARD, JULIA F · 2020 to 2024
$2.4M
NIAMS NIH HHS R01 AR077103NIAMS NIH HHS T32 AR050942
6 · The paper itself

Abstract

ObjectiveTo examine patient-reported adherence to the American College of Rheumatology (ACR) reproductive health guidelines among females of childbearing age with systemic lupus erythematosus (SLE) seen at a tertiary care center.MethodsFemales with SLE aged 18-50 years who were evaluated by a rheumatologist at a tertiary care center from January 2022 to March 2024 were invited to complete an online survey. The survey assessed whether reproductive health topics had been discussed with their rheumatologists, including: contraception, pregnancy planning (i.e., medication compatibility and disease remission), and hydroxychloroquine (HCQ) use during preconception and pregnancy. Descriptive statistics were used to summarize the characteristics of all participants and reproductive health outcomes. Exploratory bivariate analyses identified factors associated with use of effective or highly effective contraception (EHEC), contraceptive counseling, and screening for pregnancy plans among females of reproductive potential.ResultsThe cross-sectional study included 102 participants (mean age 35 years). Most participants identified as White (36.3%) or Asian/Pacific Islander (32.4%). Among participants with pregnancy history after SLE diagnosis (n = 34), most reported having pregnancy planning discussions, including HCQ use, with their rheumatologist. However, fewer than one-third of all participants reported receiving contraceptive counseling by their rheumatologist in the past year. In exploratory analyses, contraceptive counseling varied significantly by race, employment status, disease duration, and who was most likely to initiate reproductive health conversations. EHEC use varied significantly by race, with numerically higher use among White participants (59.4%).ConclusionOur findings highlight specific gaps in reproductive healthcare among females with SLE, alongside areas of high adherence with guidelines. Notable differences in contraceptive use and counseling underscore important opportunities to deliver quality care in this high-risk patient population.

Indexed as

Guideline AdherenceLupus Erythematosus, SystemicReproductive HealthAdolescentAdultContraceptionCounselingCross-Sectional StudiesFamily Planning ServicesFemaleHumansHydroxychloroquineMiddle AgedPractice Guidelines as TopicPreconception CarePregnancyHydroxychloroquinecontraceptionguidelineslupusreproductive healthrheumatic diseases

Identifiers

PMID42415627
PMCPMC13533475

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.