ArticleChemical research in toxicology2026
Analytical Identification of Novel Furan Metabolites in Human Hepatocytes and Urine: Implications for Liver and Respiratory Disease Research.
Karin R Vevang, An Trinh, Thaddeus W Schmitt, Yingchun Zhao, Linda B von Weymarn, Ellen Meier, Sarah Oppeneer Nomura, Kim Robien, Renwei Wang, Jian-Min Yuan and 1 more
Abstract read
In one paragraphArticle in Chemical research in toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Karin R VevangMasonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States.
An TrinhMasonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0009-0007-3217-6923 Thaddeus W SchmittMasonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Yingchun ZhaoMasonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Linda B von WeymarnMasonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0002-4516-4602 Ellen MeierDepartment of Psychology, University of Wisconsin-Stevens Point, Stevens Point, Wisconsin 54481, United States.
Sarah Oppeneer NomuraDivision of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Kim RobienDepartment of Exercise and Nutrition Sciences, George Washington University, Washington, District of Columbia 20052, United States.
Renwei WangUniversity of Pittsburgh Medical Center (UPMC) Hillman Cancer Center, Pittsburgh, Pennsylvania 15232, United States.
Jian-Min YuanUniversity of Pittsburgh Medical Center (UPMC) Hillman Cancer Center, Pittsburgh, Pennsylvania 15232, United States.
Lisa A PetersonMasonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0001-8715-4480 Funding
Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Timothy C. Hallstrom · 1998 to 2026
$100.4MUntargeted Analysis ResourceU2CES026533 · NIEHS · UNIVERSITY OF MINNESOTA · PI PETERSON, LISA A · 2015 to 2025
$14.0MMECHANISMS OF FURAN-INDUCED TOXICITY AND CARCINOGENICITYR01ES010577 · NIEHS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI PETERSON, LISA A · 2000 to 2011
$2.6MNCI NIH HHS P30 CA077598NIEHS NIH HHS R01 ES010577NIEHS NIH HHS U2C ES026533
6 · The paper itselfAbstract
The gas phase of tobacco smoke has been implicated as a major cause of cancer and chronic obstructive pulmonary disease. Furan, a component of the gas phase, is highly toxic and carcinogenic in rodents; however, its toxicity in humans has not been well investigated. Furan's toxicity results from cytochrome P450 2E1-catalyzed oxidation to
Indexed as
FuransHepatocytesGlutathioneHumansTandem Mass SpectrometryfuranFuransGlutathione
Identifiers
PMID42415376
PMCPMC13523489
What OpenQuestion holds
Textmetadata
Read underepoch 390