ArticleJournal of applied clinical medical physics2026
Effects of air on the dosimetric robustness of treatment plans for prostate cancer in the presence of intrafractional, anatomical changes during online adaptive radiotherapy.
Article in Journal of applied clinical medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn the online adaptive platform, a linear Boltzmann-transport-equation-solver (LBTE) as calculation algorithm is implemented for dose optimization. This class-C-optimizer is known to counteract the dose decrease at boundaries of small fields due to electronic disequilibrium by increasing the fluence to achieve the goals of dose homogeneity within the PTV. PURPOSE: To analyze the dosimetric sensitivity of adaptive treatment plans for prostate cancer to intrafractional anatomic changes in the presence of rectal air using a CBCT-based adaptive platform.
methodsIn the first part of the study planning CT scans (CT
resultsWOR within PTV∩Air-structure overlap resulted in increases of the analyzed dosimetric characteristics. D
conclusionsPTV∩Air larger than 5 mm led to LBTE-optimized treatment plans, that are sensitive to anatomic soft tissue shifts larger than 5 mm in posterior direction with respect to dose homogeneity. PTV∩Air-overlaps up to 5 mm led to LBTE-optimized treatment plans, that showed only minor sensitivities to anatomic soft tissue shifts of 2-5 mm in posterior direction with respect to dose homogeneity. During online adaptive radiotherapy, the presence of rectal air pockets or an air-filled rectal balloon did not result in clinically relevant dose increases, provided that intrafractional motion-induced soft tissue shifts remained within 5 mm in the posterior direction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.