Evidence map›Paper›PMID 42415229›Full record

ArticleBJU international2026

Automated irrigation systems in mitigating laser-induced temperature during simulated ureteroscopy.

Richard Menzies-Wilson, Jessica Williams, Candace Rhodes, Leilane Glienke, William W Roberts, Ben Turney

Abstract readComparative Study
In one paragraph

Article in BJU international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Richard Menzies-WilsonNuffield Department of Surgery, University of Oxford, Oxford, UK.ORCID 0000-0002-3449-8594
Jessica WilliamsBoston Scientific Corporation, Marlborough, MA, USA.
Candace RhodesBoston Scientific Corporation, Marlborough, MA, USA.
Leilane GlienkeDepartment of Urology, University of Michigan, Ann Arbor, MI, USA.
William W RobertsDepartment of Urology, University of Michigan, Ann Arbor, MI, USA.
Ben TurneyNuffield Department of Surgery, University of Oxford, Oxford, UK.ORCID 0000-0003-0885-6404

Funding

Boston Scientific Corporation
6 · The paper itself

Abstract

objectiveTo compare the temperature changes with laser activation when providing irrigation with a pressure bag vs a fluid management system (FMS). MATERIALS AND

methodsBenchtop experiments were performed with a LithoVue™ Elite (Boston Scientific Corp., Marlborough, MA, USA) flexible ureteroscope placed through an 11/13-F ureteric access sheath into a benchtop pelvicalyceal kidney model. Room temperature saline irrigation, via the scope, was provided either with a pressure bag or FMS. Both systems were pressurised to 200 mmHg and left for 10 min. After 10 min, a holmium:yttrium-aluminium-garnet laser was activated at 20, 40, or 60 W for 90 s. Flow rate, irrigation pressure, intrarenal pressure and calyceal temperature were recorded continuously. Experiments were repeated five times. Benchtop empirical temperature data were compared to mathematical model predictions. The mathematical model was then used to predict calyx temperature as a function of flow rate in in vivo conditions.

resultsPressure-bag irrigation flow rate declined from ~38 to ~25 mL/min (36%) over 10 min, whereas the FMS maintained stable flow of ~45 mL/min. Intrarenal pressure remained ≤30 mmHg in all experiments. Consequently, the benchtop calyx mean (standard deviation) temperature rise with pressure bag vs FMS irrigation was: at 20 W 7.9 (1.0)°C vs 6.4 (0.6)°C (P = 0.02); at 40 W 12.8 (3.2)°C vs 10.3 (1.7)°C (P = 0.15); at 60 W 17 (3.4)°C vs 12.4 (1.2)°C (P = 0.02).

conclusionIrrigation flow rate is a key determinant of thermal risk during laser lithotripsy. An automated FMS can maintain consistent flow; mitigating temperature rise and thermal dose in a benchtop model.

Indexed as

Lasers, Solid-StateTherapeutic IrrigationUreteroscopyEquipment DesignHumansTemperatureUreteroscopesFANSflow ratefluid management systemlaserpowertemperatureureteroscopy

Identifiers

PMID42415229
PMCPMC13550810

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.