Evidence map›Paper›PMID 42415216›Full record

ArticleVeterinary research2026

Genomic characterization and pathogenicity validation of Mycoplasma ovipneumoniae strains from diseased sheep: insights into potential pathogenic mechanisms of GSWW364.

Qiangsheng Lu, Jie Peng, Zongwu Ma, Lvfeng Yuan, Zhipeng Zhao, Shangdong Jia, Meijuan Tian, Huibin Tian, Xiaoxue Zhang, Qiaoying Zeng and 1 more

Abstract read
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In one paragraph

Article in Veterinary research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qiangsheng Lu *College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China.
Jie Peng *College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China. pengj@gsau.edu.cn.ORCID https://orcid.org/0000-0001-8186-1512
Zongwu MaState Key Laboratory of Herbage Improvement and Grassland Agro-Ecosystems; Key Laboratory of Grassland Livestock Industry Innovation, Ministry of Agriculture and Rural Affairs, Engineering Research Center of Grassland Industry, Ministry of Education, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, China.
Lvfeng YuanLanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.
Zhipeng ZhaoCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China.
Shangdong JiaCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China.
Meijuan TianCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China.
Huibin TianState Key Laboratory of Herbage Improvement and Grassland Agro-Ecosystems; Key Laboratory of Grassland Livestock Industry Innovation, Ministry of Agriculture and Rural Affairs, Engineering Research Center of Grassland Industry, Ministry of Education, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, China.
Xiaoxue ZhangCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.
Qiaoying ZengCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China.
Weimin WangState Key Laboratory of Herbage Improvement and Grassland Agro-Ecosystems; Key Laboratory of Grassland Livestock Industry Innovation, Ministry of Agriculture and Rural Affairs, Engineering Research Center of Grassland Industry, Ministry of Education, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, China.

Funding

Gansu Provincial Science and Technology Major Project Funding 26ZDNA003National Natural Science Foundation of China 3244100920
6 · The paper itself

Abstract

Mycoplasma ovipneumoniae (Mo) is the primary etiological agent of mycoplasmal pneumonia of sheep in China, posing a significant threat to the sheep industry. In this study, 18 strains of Mo were isolated from nasal swab samples collected from diseased Hu sheep at nine farms in Gansu Province. Nine representative strains were selected for whole-genome sequencing (WGS) and analysis to explore the genetic relationships between the isolates and reference strains from different regions and hosts. On the basis of the cultural characteristics and the genetic variability among regional strains, strain GSWW364 was chosen for further experiments. A total of 100 healthy 2-month-old Hu sheep were challenged experimentally with strain GSWW364 at a dose of 1 × 10

Indexed as

Genome, BacterialMycoplasma ovipneumoniaePneumonia, MycoplasmaSheep DiseasesAnimalsChinaSheepVirulenceWhole Genome Sequencinggenomic characterizationhost pathogenesisHu sheepMo GSWW364Mycoplasma ovipneumoniae

Identifiers

PMID42415216
PMCPMC13339553

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.