ReviewRespiratory research2026
Lung organoids and organ-on-a-chip models in respiratory disease research: advances, applications, and challenges.
Review in Respiratory research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Lung organoids are human-derived in vitro models that can form three-dimensional structures in culture. They provide useful systems for respiratory disease research. This review first outlines the main cell sources and construction methods for lung organoids. It then discusses how these models have been used to study pulmonary fibrosis, lung cancer, chronic obstructive pulmonary disease (COPD), and respiratory infections. The review also explains how organ-on-a-chip technology can add flow, stretch, and other physical cues to organoid models. These cues help researchers build more dynamic systems, but they do not remove the need for careful validation. Finally, this review summarizes key challenges in standardization, model complexity, and clinical translation. It also describes future directions for personalized and precision respiratory medicine.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.