Evidence map›Paper›PMID 42415037›Full record

ArticleCost effectiveness and resource allocation : C/E2026

The economic impact of a physician-introduced web portal on lower back pain: results from a cluster-randomized trial.

Klaus Kaier, Christian Schlett, Piet van der Keylen, Renate Lange, Andrea C Schöpf-Lazzarino, Martin Boeker, Mirjam Körner, Andy Maun, Sebastian Voigt-Radloff, Erik Farin-Glattacker

Abstract read
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Article in Cost effectiveness and resource allocation : C/E, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Klaus KaierInstitute of Medical Biometry and Statistics, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. klaus.kaier@gmail.com.
Christian SchlettSection of Health Care Research and Rehabilitation Research, Medical Center - University of Freiburg, Faculty of Medicine, Freiburg, Germany.
Piet van der KeylenInstitute of General Practice, Friedrich-Alexander University Erlangen-Nürnberg, University Hospital Erlangen, Erlangen, Germany.
Renate LangeBKK Landesverband Bayern, Munich, Germany.
Andrea C Schöpf-LazzarinoCareum School of Health, Zurich, Switzerland.
Martin BoekerInstitute for Artificial Intelligence and Informatics in Medicine, Technical University of Munich, Munich, Germany.
Mirjam KörnerInstitute of Medical Psychology and Medical Sociology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Andy MaunInstitute of General Practice / Family Medicine, Medical Center - University of Freiburg, Faculty of Medicine, Freiburg, Germany.
Sebastian Voigt-RadloffInstitute for Evidence in Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Erik Farin-GlattackerSection of Health Care Research and Rehabilitation Research, Medical Center - University of Freiburg, Faculty of Medicine, Freiburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLow back pain (LBP) is a prevalent condition that imposes a significant economic burden on healthcare systems. Digital health interventions, such as the web-based tala-med platform, offer an evidence-based approach to patient education and shared decision-making. This study evaluates the financial and cost-effectiveness implications of integrating tala-med into primary care compared to routine care.

methodsThis multi-center, cluster-randomized trial assigned primary care practices (PCPs) in Germany to either an intervention group (IG) using tala-med or a control group (CG) providing routine care. Patients aged ≥ 18 with LBP were recruited and health economic evaluation included a claims-data-based cost analysis of back pain-related healthcare utilization for a three month follow-up. Cost-effectiveness was assessed by comparing additional costs per unit increase in self-reported knowledge and perceived informedness. LBP knowledge ranged from 1 (very low) to 5 (very high) and LBP informedness ranged from 1 (not at all) to 5 (very good). Sensitivity analyses included also non-back-pain related healthcare utilization and restricted the analysis to a sub-cohort of currently employed patients.

resultsData from 183 intervention and 133 control patients were analysed. The intervention group demonstrated fewer general practitioner (risk-adjusted incidence rate ratio (IRR): 0.86, p = 0.284) and specialist contacts (IRR 0.70, p = 0.009), but significantly more back pain-related sick leave (IRR 8.73, p = 0.001). The adjusted increase in back pain-related costs in the IG was €822.22 (p = 0.005). Sensitivity analyses showed minimal impact on total healthcare costs (€145.88, p = 0.819). Cost-effectiveness analysis indicated additional costs of €3328.54 per unit increase in self-reported knowledge and €1611.21 per unit increase in perceived informedness. DISCUSSION: While tala-med use was associated with increased back pain-related costs, total healthcare expenditures remained stable. The reasons for the discrepancy remain unclear but may include increased awareness of LBP or extended recovery periods facilitated by sick leave. Further research is needed to validate these findings and explore the long-term benefits of digital health interventions in LBP management.

Identifiers

PMID42415037
PMCPMC13343678

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.