Evidence map›Paper›PMID 42414954›Full record

ArticleBMC ophthalmology2026

Comparative outcomes of cryoextraction and conventional extraction in anterior and lateral orbitotomy for orbital cavernous venous malformations (so-called cavernous hemangioma).

Joris De Keersmaecker, Luciano Accetta, David Muallah, Hendrik Schulz, Eckart Bertelmann

Abstract readComparative Study
In one paragraph

Article in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Joris De KeersmaeckerDepartment of Ophthalmology, Charité - Universitätsmedizin Berlin, Berlin, Germany. joris.de-keersmaecker@charite.de.ORCID https://orcid.org/0000-0002-1169-6168
Luciano AccettaDepartment of Ophthalmology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
David MuallahDepartment of Ophthalmology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Hendrik SchulzDepartment of Ophthalmology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Eckart BertelmannDepartment of Ophthalmology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComparison of surgical outcomes of lateral orbitotomy and transconjunctival anterior orbitotomy using the swinging eyelid approach for cavernous venous malformations (CVM), with and without cryoextraction.

methodsIn this single-center, retrospective case series (2005-2024), a single surgeon performed CVM excisions. Operative time and postoperative complications were compared across surgical approaches and extraction techniques for a cohort of 60 patients.

resultsLateral orbitotomy was performed in 25 patients (14 conventional, 11 cryo-assisted) and the swinging eyelid approach in 35 patients (16 conventional, 19 cryo-assisted). In the swinging eyelid group, cryoextraction significantly reduced operative time (49.0 vs. 59.0 min, p = 0.04). A similar trend was observed in the lateral orbitotomy group, although the difference was not statistically significant (81.0 vs. 101.5 min, p = 0.23). Postoperatively, visual acuity remained stable or improved in 97% of patients. Diplopia occurred less frequently following cryo-assisted extraction and was transient in most cases, with persistent diplopia requiring further intervention occurring exclusively after conventional extraction.

conclusionsCryoextraction is associated with shorter operative times and favorable functional outcomes in the surgical management of orbital cavernous venous malformations, particularly when using the swinging eyelid approach. When applied in appropriately selected cases, cryoextraction represents a safe and effective technique that may reduce surgical manipulation and postoperative morbidity.

Indexed as

CryosurgeryHemangioma, CavernousOphthalmologic Surgical ProceduresOrbitOrbital NeoplasmsAdolescentAdultAgedChildFemaleHumansMaleMiddle AgedOperative TimeRetrospective StudiesTreatment OutcomeAnterior orbitotomyCavernous hemangiomaCavernous venous malformationCryoextractionLateral orbitotomySurgical outcomesSwinging eyelid approach

Identifiers

PMID42414954
PMCPMC13343621

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