ArticleBMC psychiatry2026
dDual-target rTMS treatment for adolescent depression with headache: a case report.
Article in BMC psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundAdolescent patients with major depressive disorders (MDD) frequently co-occur with headache, contributing to substantial disease burden and social functional impairment. Repetitive transcranial magnetic stimulation (rTMS) has been supported for MDD and pain conditions, but clinical evidence for a combined affect and pain network targeting strategy in comorbid phenotypes remains limited. CASE PRESENTATION: A 16-year-old male student presented with a 2-year history of depression accompanied by paroxysmal headache. We administered a dual-target rTMS protocol targeting the dorsolateral prefrontal cortex and primary motor cortex. After 2 weeks of treatment (40 sessions), the patient's depressive and headache symptoms improved significantly.
conclusionsThis case suggests that an intensified dual-target rTMS approach engaging both affect regulation and pain modulation targets may be feasible for adolescents with comorbid depression and headache. Prospective studies are needed to determine optimal parameters, durability, and safety. CLINICAL TRIAL NUMBER: Not applicable.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.