ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2026
Impact of post-total thyroidectomy thyroglobulin levels on recurrence in patients with differentiated thyroid cancer at a tertiary care center in Mexico.
Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionUp to 30% of patients with differentiated thyroid carcinoma may experience recurrence within the first decade following initial treatment. Therefore, highly sensitive markers such as thyroglobulin (Tg) are vitally important for detecting persistent or recurrent disease and treating it in a timely manner. In our population, there are few epidemiological records with which to validate cut-off points and compare them with other clinicopathological risk factors.
objectiveTo evaluate the relationship between post-total thyroidectomy Tg levels and medium-term recurrence after surgery in patients with papillary thyroid cancer. MATERIALS AND
methodsThe levels of non-stimulated thyroglobulin 4-12 weeks after surgery were measured in 106 patients treated between 2018 and 2022 in the Surgical Oncology Department.
resultsThe recurrence rate was of 44%. Univariate analysis showed statistical significance for histologic type, ATA risk of recurrence, and thyroglobulin level, but multivariate analysis revealed a positive association only for patients classified as high risk and for those with non-stimulated Tg levels between 1.1 and 10, which is consistent with previous studies.
conclusionBoth clinical-pathological risk stratification and levels of unstimulated postoperative serum thyroglobulin are useful for predicting structural recurrence even in settings with a high prevalence of aggressive histological variants. Therefore, active surveillance protocols based on these factors are essential for achieving good long-term outcomes and avoiding unnecessary diagnostic tests or surgical interventions in patients with differentiated thyroid cancer.
Indexed as
Identifiers
42414843What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.