Evidence map›Paper›PMID 42414768›Full record

Observational studySurgical endoscopy2026

Comparison of the perioperative outcomes between uniportal thoracoscopic lobectomy and segmentectomy for early-stage non-small-cell lung cancer in Japan.

Hitoshi Igai, Takuya Watanabe, Takahiro Homma, Takashi Suda, Toshiaki Morikawa

Abstract readComparative StudyMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hitoshi IgaiDepartment of General Thoracic Surgery, Japanese Red Cross Maebashi Hospital, 389-1 Asakura-cho, Maebashi, Gunma, 371-0811, Japan. hitoshiigai@gmail.com.ORCID http://orcid.org/0000-0002-5916-8209
Takuya WatanabeDivision of Thoracic Surgery, Respiratory Disease Center, Seirei Mikatahara General Hospital, 3453, Mikatahara-Cho, Chuo-Ku, Hamamatsu, 433-8558, Japan.
Takahiro HommaDepartment of Thoracic Surgery, St. Marianna University School of Medicine, 2-16-1 Sugao, Kawasaki, Kanagawa, 216-8511, Japan.
Takashi SudaDepartment of Thoracic Surgery, Fujita Health University Okazaki Medical Center, 1 Gotanda, Harisaki, Okazaki, Aichi, 444-0827, Japan.
Toshiaki MorikawaDepartment of General Thoracic Surgery, Tokyo General Hospital, 3-15-2 Egota, Nakano-Ku, Tokyo, 165-0022, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSegmentectomy performed via a uniportal thoracoscopic approach is considered technically more challenging than lobectomy, and its adoption in Japan has not yet been well characterized. This study aimed to assess the safety and feasibility of uniportal thoracoscopic segmentectomy compared with lobectomy through a multicenter retrospective analysis conducted by the Japan Uniportal Video-assisted Thoracoscopic Surgery Interest Group.

methodsWe retrospectively analyzed patients who underwent uniportal thoracoscopic anatomical lung resection at 43 institutions in Japan between April 2018 and March 2023. Patients with clinical stage 0/IA non-small-cell lung cancer were included. Stabilized inverse probability of treatment weighting (IPTW) based on propensity scores was used to adjust for differences in baseline characteristics between the segmentectomy and lobectomy groups. The primary endpoint was the rate of surgical procedure-related complications, and secondary endpoints included other perioperative outcomes.

resultsA total of 2,530 eligible patients were identified, including 1,807 who underwent lobectomy and 723 who underwent segmentectomy. Both the overall number of cases and the proportion of segmentectomies increased annually during the study period. After stabilized IPTW, postoperative drainage duration (P = 0.005) and postoperative hospital stay (P = 0.002) favored segmentectomy, whereas operative time (P = 0.527) and blood loss (P = 0.347) were not significantly different. Clavien-Dindo grade ≥ III morbidity (OR: 0.69, 95% CI: 0.49-0.97, P = 0.031) and 30-day readmission (OR: 0.19, 95% CI: 0.06-0.62, P = 0.006) were lower after segmentectomy. Surgical procedure-related complications were comparable between groups after IPTW (OR: 0.89, 95% CI: 0.69-1.16, P = 0.398).

conclusionsIn this nationwide multicenter registry, uniportal thoracoscopic segmentectomy was associated with short-term perioperative outcomes comparable to lobectomy after IPTW adjustment. These findings should be interpreted as real-world perioperative evidence within the registry setting and do not address long-term oncologic outcomes.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsPneumonectomyThoracic Surgery, Video-AssistedAgedFeasibility StudiesFemaleHumansJapanLength of StayMaleMiddle AgedNeoplasm StagingOperative TimePostoperative ComplicationsRetrospective StudiesComplicationsPulmonary lobectomyPulmonary segmentectomyUniportal thoracoscopic approach

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.