Evidence map›Paper›PMID 42414638›Full record

ArticleAesthetic plastic surgery2026

Modified Hotz Operation Combined with Modified Medial Canthoplasty to Correct Congenital Lower Eyelid Epiblepharon in a Chinese Population.

Sixu Ren, Bingtao Li, Yu Wen, Li'ang Xiao, Qianqian Guo, Yimin Wu, Rui Tian

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Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Sixu RenDepartment of Ophthalmology, the Second Hospital of Jilin University, Changchun, 130041, Jilin Province, China.
Bingtao LiDepartment of Ophthalmology, the Second Hospital of Jilin University, Changchun, 130041, Jilin Province, China.
Yu WenPatient Service Center, the Second Hospital of Jilin University, Changchun, 130041, Jilin Province, China.
Li'ang XiaoDepartment of Ophthalmology, the Second Hospital of Jilin University, Changchun, 130041, Jilin Province, China.
Qianqian GuoDepartment of Ophthalmology, the Second Hospital of Jilin University, Changchun, 130041, Jilin Province, China.
Yimin WuDepartment of Ophthalmology, the Second Hospital of Jilin University, Changchun, 130041, Jilin Province, China.
Rui TianDepartment of Ophthalmology, the Second Hospital of Jilin University, Changchun, 130041, Jilin Province, China. tianrui@jlu.edu.cn.

Funding

Jilin Province Health Talent Special Program 2024WSZX-C04Jilin Province Health Talent Special Program 2025WSZX-ZH05
6 · The paper itself

Abstract

backgroundEpiblepharon correction combined with epicanthoplasty is useful for the treatment of congenital lower eyelid epiblepharon (CE). To further refine this approach, we developed a modified medial canthoplasty (Mod-MC) involving removal of the medial canthus fibrous band (MCFB), combined with a modified Hotz procedure (Mod-Hotz). This study aimed to evaluate the efficacy of Mod-Hotz + Mod-MC in Chinese patients and to investigate the role of the MCFB in surgical outcomes.

methodsPatients diagnosed with CE were divided into two groups according to the surgical procedure performed: Mod-Hotz + Mod-MC and Mod-Hotz. Postoperative outcomes were compared between the two groups and analyzed statistically. The histopathological structure and ultrastructure of the MCFB were examined to analyze its correlation with surgical outcomes.

resultsThe cure rate was similar between the two groups in the 1month postoperative period. The recurrence rate in the Mod-Hotz + Mod-MC group was significantly lower than that in the Mod-Hotz group 12 months postoperatively. Ultrastructurally, the MCFB consisted of disorganized collagen and striated muscle with evidence of dissolution. Mitochondrial accumulation and vacuolation within muscle cells indicated significant structural and metabolic dysfunctions.

conclusionsThe postoperative efficacy of Mod-Hotz + Mod-MC was more stable than Mod-Hotz alone. We suspected that the removal of the MCFB could eliminate abnormal fibrous tissue, minimize scar formation, and release abnormal vertical skin tension at the medial canthus, thereby helping maintain the stability of surgical effect. LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

BlepharoplastyEyelid DiseasesEyelidsChildChild, PreschoolChinaEast Asian PeopleFemaleFollow-Up StudiesHumansMaleRetrospective StudiesTreatment OutcomeCongenital lower eyelid epiblepharonEpicanthusMedial canthal fibrous bandModified Hotz operationModified medial canthoplastyUltrastructure

Identifiers

PMID42414638

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.