Evidence map›Paper›PMID 42414596›Full record

ArticleJournal of neuro-oncology2026

Visual outcomes of sight threatening radiation-induced meningiomas after low-dose head irradiation: tinea capitis as a paradigm.

Dahlia Palevski, Hadas Stiebel-Kalish, Omer Yizhach Bialer

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Article in Journal of neuro-oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Dahlia PalevskiOphthalmology Department, Rabin Medical Center, 39 Jabotinski St., Petach-Tikva, Israel.
Hadas Stiebel-KalishOphthalmology Department, Rabin Medical Center, 39 Jabotinski St., Petach-Tikva, Israel.
Omer Yizhach BialerOphthalmology Department, Rabin Medical Center, 39 Jabotinski St., Petach-Tikva, Israel. omer.bialer@gmail.com.ORCID http://orcid.org/0000-0002-9979-7990

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the visual characteristics and prognosis of vision-threatening meningiomas following low dose head radiation and compare them to those of primary unexposed meningiomas.

methodsA retrospective cohort of adults with meningiomas adjacent to the optic nerves or intracranial visual pathways was categorized into radiation-exposed and unexposed meningiomas. Data collected included demographics, visual biomarkers at presentation and at final follow-up, including Visual Acuity (VA), color vision (CV), Visual Field (VF) and peripapillary Retinal Nerve Fiber Layer (RNFL) thickness via Optical coherence tomography (OCT). Comparative analyses were performed between radiation-exposed and unexposed cohorts.

results289 eligible patients seen between 2004 and 2023 were included, out of which 31 (10.7%) had undergone tinea capitis radiation. At presentation, patients exhibited a median BCVA of 0.1 LogMAR [IQR 0.1-0.6], median CV of 100% [IQR 64.5%-100%], and 9 (29%) had normal visual fields. Notably, 16 (51.61%) experienced visual loss. Their BCVA decreased at final follow-up, to median 0.23 [IQR 0.1-1.46]. Comparative analysis with 114 radiation-naïve patients with meningioma-induced visual loss revealed no statistically significant disparities in visual characteristics at presentation or at follow-up.

conclusionsNo statistically significant differences in clinical presentation or visual prognosis were detected between patients with visual pathway meningiomas exposed to low-dose childhood radiation and radiation-naïve patients. Since low-dose cranial irradiation continues to be widely used for conditions such as thyroid eye disease, our findings are relevant beyond the specific context of tinea capitis.

Indexed as

Cranial IrradiationMeningeal NeoplasmsMeningiomaNeoplasms, Radiation-InducedTinea CapitisVision DisordersAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRetrospective StudiesVisual AcuityMeningiomaRadiationRadiation-induced meningiomaTinea capitis

Identifiers

PMID42414596
PMCPMC13342210

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.