Evidence map›Paper›PMID 42414200›Full record

ArticleJournal of voice : official journal of the Voice Foundation2026

Creak Derived from CAPE-V Sentences in Patients with AdLd and pMTD.

Rachel Norotsky, Kelly Zdrowak, Katherine L Marks

Abstract read
In one paragraph

Article in Journal of voice : official journal of the Voice Foundation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Rachel NorotskyEmory University School of Medicine, Atlanta, Georgia.
Kelly ZdrowakUniversity of California San Francisco, San Francisco, California, USA.
Katherine L MarksEmory University School of Medicine, Atlanta, Georgia. Electronic address: katie.marks@emory.edu.

Funding

Acoustic and Physiological Outcome Measures for Laryngeal DystoniaR21DC023280 · NIDCD · EMORY UNIVERSITY · PI MARKS, KATHERINE LINDSEY · 2025 to 2025
$468k
NIDCD NIH HHS R21 DC023280
6 · The paper itself

Abstract

objectiveThe purpose of this study was to evaluate whether acoustic creak (%) derived from the Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V) sentences differentiates adductor laryngeal dystonia (AdLD) from primary muscle tension dysphonia (pMTD).

methodsIn this retrospective study, acoustic recordings from 42 patients (21 with AdLD and 21 with pMTD) at a tertiary voice center were analyzed. Participants produced six CAPE-V sentences during a standardized voice evaluation. Recordings were segmented and analyzed using an automated algorithm to compute percent creak (%), defined as creak duration relative to total voicing duration. Smoothed cepstral peak prominence (CPP) was also extracted. Hierarchical binomial logistic regression models evaluated whether creak alone or creak in combination with CPP predicted the diagnostic group.

resultsMean creak (%) values were comparable between groups. Creak (%) did not significantly predict the diagnostic group (P > 0.05). Inclusion of CPP did not improve model performance. Creak distributions were positively skewed in both groups, with notable interindividual variability.

conclusionCreak derived from CAPE-V sentences does not differentiate AdLD from pMTD. These findings suggest that stimulus characteristics, particularly sentence length and the associated respiratory-phonatory demands, may influence the discriminative validity of creak. Further research is required to clarify its clinical utility across speech tasks.

Indexed as

Acoustic analysisCAPE-VCreakLaryngeal dystoniaMuscle tension dysphonia

Identifiers

PMID42414200
PMCPMC13348723

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.