Evidence map›Paper›PMID 42414103›Full record

Observational studyJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2026

Association of dental diseases with pulmonary outcomes in a multicenter cohort of adolescents and young adults with CF.

Margaret Rosenfeld, Lloyd Mancl, Noel K Childers, Sundass Khan, Isabel Virella-Lowell, Patricia McCurdy, Sharon McNamara, Marianne S Muhlebach, Marissa Nelsen, Josh Orack and 6 more

Abstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Margaret RosenfeldCenter for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle, WA USA; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA USA. Electronic address: Margaret.rosenfeld@seattlechildrens.org.
Lloyd ManclDepartment of Oral Health Sciences, University of Washington School of Dentistry, Seattle, WA USA.
Noel K ChildersDepartment of Pediatric Dentistry, University of Alabama at Birmingham, Birmingham, AL USA.
Sundass KhanDepartment of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC USA.
Isabel Virella-LowellDepartment of Pediatrics, University of Alabama at Birmingham, Birmingham, AL USA.
Patricia McCurdyDepartment of Pediatric Dentistry, University of Alabama at Birmingham, Birmingham, AL USA.
Sharon McNamaraCenter for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle, WA USA.
Marianne S MuhlebachDepartment of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC USA; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC USA.
Marissa NelsenCenter for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle, WA USA.
Josh OrackDepartment of Oral Health Sciences, University of Washington School of Dentistry, Seattle, WA USA.
Marilyn RothenDepartment of Oral Health Sciences, University of Washington School of Dentistry, Seattle, WA USA.
Apoena RibeiroDepartment of Orofacial Sciences, School of Dentistry, University of California at San Francisco, San Francisco, CA USA.
Matthew WolfgangDepartment of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC USA; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC USA.
Lindsey YapDepartment of Oral Health Sciences, University of Washington School of Dentistry, Seattle, WA USA.
Alaa A AlkhateebDental Health Department, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Donald L ChiDepartment of Oral Health Sciences, University of Washington School of Dentistry, Seattle, WA USA.

Funding

Understanding Oral Diseases in Cystic Fibrosis to Develop Tailored Preventive Dental Interventions.U01DE030418 · NIDCR · UNIVERSITY OF WASHINGTON · PI KIM, AMY S, ROSENFELD, MARGARET · 2021 to 2025
$3.7M
NIDCR NIH HHS U01 DE030418
6 · The paper itself

Abstract

CF is associated with multiple risk factors for caries and gingivitis, which in turn are potential risk factors for poor lung health, mediated through aspiration of dysbiotic oral microbiota. Nonetheless, the association between dental diseases and respiratory outcomes in CF has not previously been evaluated. Here, we report the baseline cross-sectional associations between dental diseases (caries and gingivitis) and respiratory outcomes (FEV

Indexed as

Cystic FibrosisDental CariesGingivitisAdolescentAdultChildCross-Sectional StudiesFemaleHumansMaleProspective StudiesRespiratory Function TestsRisk FactorsYoung Adult

Identifiers

PMID42414103
PMCPMC13399736

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.