Trial reportRespirology (Carlton, Vic.)2026
The SINFONIA Study: A Randomised Controlled Trial to Determine Feasibility and Effectiveness of Online Group Singing for People With COPD or ILD and Breathlessness.
Trial report in Respirology (Carlton, Vic.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The SINFONIA Study: A Randomised Controlled Trial to Determine Feasibility and Effectiveness of Online Group Singing for People With COPD or ILD and Breathlessness.Respirology (Carlton, Vic.) · 2026Trial
- Non-pharmacological Management of Fibrosing Interstitial Lung Diseases.Tuberculosis and respiratory diseases · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
BACKGROUND AND
objectivePeople with chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) experience chronic breathlessness and reduced quality of life (QOL). Specialised singing programs for people with lung disease may improve QOL and symptoms.
methodsA randomised controlled trial conducted in Australia to determine the feasibility and effectiveness of 12 weeks of online, guided group singing on QOL (primary outcome, as measured by SF36), as compared to usual care in people with COPD or ILD. SECONDARY OUTCOMES: anxiety, depression, dyspnoea and loneliness. Intervention effectiveness was assessed using mixed effects linear regression.
resultsOne hundred and one participants were randomised (50 singing, 51 control; 64 COPD, 37 ILD; mean age 69.6 years; 74% women; 42% mMRC = 2, 58% mMRC ≥ 3). The results of the primary endpoint were a mean treatment effect (MTE) of singing of 2.5 points (95% CI -1.9 to 6.8; p = 0.266) on SF-36 mental health score (MCS) and 2.6 points (95% CI -0.9 to 6.1; p = 0.138) on the physical component score (PCS), neither of which were statistically or clinically significant. In the per-protocol analysis, significant improvement in MCS was detected in participants who attended 8 or more sessions (MTE:4.8; 95% CI 0.1 to 9.5; p = 0.047). No significant effects on secondary outcomes were detected. No adverse events were reported.
conclusionsThis RCT demonstrated that online group singing is a feasible intervention for people with COPD or ILD and breathlessness. Although the intention-to-treat analysis did not demonstrate effectiveness, per-protocol analyses suggest that singing may improve mental health components of QOL in people with COPD or ILD.
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