Evidence map›Paper›PMID 42413137›Full record

ArticleJournal of the American Medical Directors Association2026

Impact of COVID-19 Lockdown on Depressive and Behavioral Symptoms in US Nursing Home Residents.

Yiyang Yuan, Jonggyu Baek, Kate L Lapane

Abstract read
In one paragraph

Article in Journal of the American Medical Directors Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yiyang YuanDivision of Epidemiology, Department of Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, MA, USA. Electronic address: Yiyang.Yuan@umassmed.edu.
Jonggyu BaekDivision of Biostatistics and Health Services Research, Department of Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Kate L LapaneDivision of Epidemiology, Department of Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, MA, USA.

Funding

Social Connectedness and Social Isolation in Nursing Home ResidentsR01AG071692 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Kate L Lapane · 2021 to 2026
$4.1M
NIA NIH HHS R01 AG071692
6 · The paper itself

Abstract

objectivesTo examine the short-term within-individual changes in residents' depressive and behavioral symptoms following the March 2020 lockdown in US nursing homes.

designRetrospective cohort study. SETTING AND

participantsNursing home residents in US nursing homes operating from 2019 to 2020.

methodsResidents in 2020 were considered exposed to the lockdown, and residents in 2019 were considered not exposed to the lockdown. Using the national Minimum Data Set 3.0, outcomes included changes in depressive symptoms (Patient Health Questionnaire [PHQ]-9 or PHQ-10-OV) and behavioral symptoms (Agitated and Reactive Behavior Scale), examined as continuous score changes and binary adverse severity changes between baseline and follow-up (PHQ-9: n

resultsNo clinically meaningful within-individual, short-term changes in depressive or behavioral symptom scores were observed. Associations did not meaningfully differ across resident cognitive impairment levels, facility characteristics, or states with visitation bans. For residents with minimal or mild depressive symptoms at baseline, those exposed to the lockdown were 22% and 39% more likely to experience worsening symptoms than those unexposed, whereas those with very severe behavioral symptoms at baseline were 7% less likely to show no improvement. These associations were slightly stronger in states with visitation bans. CONCLUSIONS AND IMPLICATIONS: Findings should be interpreted with measurement sensitivity, residents' lived experiences, and nursing home efforts to address social isolation in mind, underscoring the need for more responsive and timely assessments and for balanced approaches that consider both infection control and residents' psychosocial well-being.

Indexed as

Behavioral SymptomsCOVID-19DepressionNursing Home ResidentsNursing HomesAgedAged, 80 and overFemaleHumansMaleRetrospective StudiesSARS-CoV-2United Statesbehavioral symptomsCOVID-19Depressive symptomsMinimum Data Setnursing homevisitation restriction

Identifiers

PMID42413137
PMCPMC13344163

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.