Evidence map›Paper›PMID 42412768›Full record

ArticlePLOS digital health2026

Designing user-centered evaluations: Leveraging beta-testing results to develop process evaluation interview questions for the AMPLIFY program.

Jami L Anderson, Laura Q Rogers, Wendy Demark-Wahnefried, Michelle Y Martin, Maria Pisu, Yu-Mei Schoenberger-Godwin, Dorothy W Pekmezi, Ivan I Herbey, Kevin R Fontaine, Kelly Kenzik and 5 more

Abstract read
In one paragraph

Article in PLOS digital health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jami L AndersonDepartment of Family and Community Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.ORCID https://orcid.org/0000-0001-9203-765X
Laura Q RogersDivision of General Internal Medicine and Population Science, Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.ORCID https://orcid.org/0000-0003-4216-8381
Wendy Demark-WahnefriedO'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Michelle Y MartinDepartment of Preventive Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America.
Maria PisuDivision of General Internal Medicine and Population Science, Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Yu-Mei Schoenberger-GodwinDivision of General Internal Medicine and Population Science, Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Dorothy W PekmeziO'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Ivan I HerbeyDepartment of Surgery, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Kevin R FontaineO'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Kelly KenzikDepartment of Surgery, Brigham and Women's Hospital, Harvard University, Boston, Massachusetts, United States of America.
Robert A OsterDivision of General Internal Medicine and Population Science, Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Larry HearldDepartment of Health Services Administration, School of Health Professions, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Tapan MehtaDepartment of Family and Community Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
John WaterborDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Nataliya V IvankovaDepartment of Health Services Administration, School of Health Professions, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Omer Jamy · 1985 to 2026
$165.9M
Recruitment and Biostatistics (R & B) SRC Core Co-Leads: Pisu and OsterP01CA229997 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Wendy Demark-Wahnefried, LAURA Q ROGERS · 2018 to 2026
$17.1M
UAB Cancer Prevention and Control Training Program (T32)T32CA047888 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Ritu Aneja, Ellen Mary Lavoie Smith · 2018 to 2026
$3.2M
NCI NIH HHS P01 CA229997NCI NIH HHS P30 CA013148NCI NIH HHS T32 CA047888
6 · The paper itself

Abstract

Refining digital health programs with end-user feedback is essential throughout program lifecycles to ensure user-centered perspectives are incorporated during all program development. Results from beta-testing "think aloud" interviews exploring program engagement, satisfaction, motivation, and usefulness may be leveraged to support development of interview questions for a subsequent user-centered process evaluation implemented during program efficacy testing. We describe how results from beta-testing "think aloud" interviews were utilized to inform the design of user-centered process evaluation interview questions for implementation during program efficacy testing of AMPLIFY, a web-based diet and exercise program for older cancer survivors. Beta-testers (n = 15) were asked to complete three "think aloud" interviews via a videoconference platform over a 6-month period; 40 interviews were completed, accounting for early dropouts. Transcripts were analyzed using a multi-step process: 1) suggested refinements from beta-testing "think aloud" interview results were catalogued and organized according to whether the program feature was liked, disliked, or confusing to the beta-tester; and 2) suggestions for refinements were categorized based on feasibility to adopt (feasible/not feasible), the type of recommended change (formatting/content), and underlying improvement goal (engagement, satisfaction, motivation, usefulness). Refinements considered feasible to adopt were categorized into formatting refinements (changes to the presentation/organization of the program) and content refinements (additions, deletions, or changes to the information provided in the program). Refinements were also categorized by relationship to four process evaluation constructs: engagement, satisfaction, motivation, and usefulness. Results informed user-centered process evaluation interview questions for implementation during program efficacy testing; such that, subsequent semi-structured interview questions were developed based on these evaluation constructs and underlying improvement goals. The application of beta-testing results to refinements and process evaluation provide a potential guide for other researchers developing and evaluating digital health interventions.

Identifiers

PMID42412768
PMCPMC13340835

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.