ArticleJournal of applied physiology (Bethesda, Md. : 1985)2026
Impact of Baydur ratio correction on the reliability of esophageal pressure measurement.
Andrea Restivo, Michele Delle Vergini, Genevieve McCormack, Timothy G Gaulton, Glasiele Alcala, Davide Raimondi Cominesi, Elisa Mereto, Sarah E Gerard, Rehab Khalid, Rajiv Gupta and 7 more
Abstract read
In one paragraphArticle in Journal of applied physiology (Bethesda, Md. : 1985), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
17 authors.
Andrea RestivoAnesthesia Center for Critical Care Research, Department of Anaesthesiology, Critical Care and Pain Medicine, Mass General Brigham and Harvard Medical School, Boston, Massachusetts, United States.ORCID 0009-0005-9489-1952 Michele Delle VerginiAnesthesia Center for Critical Care Research, Department of Anaesthesiology, Critical Care and Pain Medicine, Mass General Brigham and Harvard Medical School, Boston, Massachusetts, United States.ORCID 0009-0002-0060-4325 Genevieve McCormackAnesthesia Center for Critical Care Research, Department of Anaesthesiology, Critical Care and Pain Medicine, Mass General Brigham and Harvard Medical School, Boston, Massachusetts, United States.
Timothy G GaultonAnesthesia Center for Critical Care Research, Department of Anaesthesiology, Critical Care and Pain Medicine, Mass General Brigham and Harvard Medical School, Boston, Massachusetts, United States.ORCID 0000-0002-3111-1972 Glasiele AlcalaDivision of Respirology, Department of Medicine, University Health Network, Toronto, Ontario, Canada.ORCID 0000-0002-0727-1132 Elisa MeretoAnesthesia Center for Critical Care Research, Department of Anaesthesiology, Critical Care and Pain Medicine, Mass General Brigham and Harvard Medical School, Boston, Massachusetts, United States.
Sarah E GerardRoy J. Carver Department of Biomedical Engineering, University of Iowa, Iowa City, Iowa, United States.ORCID 0000-0001-8101-3150 Rehab KhalidDepartment of Radiology, Mass General Brigham and Harvard Medical School, Boston, Massachusetts, United States.ORCID 0000-0002-0935-058X Rajiv GuptaDepartment of Radiology, Mass General Brigham and Harvard Medical School, Boston, Massachusetts, United States.ORCID 0000-0002-5882-960X Lorenzo BerraAnesthesia Center for Critical Care Research, Department of Anaesthesiology, Critical Care and Pain Medicine, Mass General Brigham and Harvard Medical School, Boston, Massachusetts, United States.ORCID 0000-0003-2702-2093 Yi XinAnesthesia Center for Critical Care Research, Department of Anaesthesiology, Critical Care and Pain Medicine, Mass General Brigham and Harvard Medical School, Boston, Massachusetts, United States.
Marcus Henrique VictorElectronics Engineering Division, Aeronautics Institute of Technology, Sao Paulo, Brazil.ORCID 0000-0002-5928-0591 Marcelo B P AmatoUnidade de Terapia Intensiva Respiratoria, Divisao de Pneumologia, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil.
Jason H T BatesDivision of Pulmonary and Critical Care, Department of Medicine, University of Vermont, Burlington, Vermont, United States.
Maurizio CeredaAnesthesia Center for Critical Care Research, Department of Anaesthesiology, Critical Care and Pain Medicine, Mass General Brigham and Harvard Medical School, Boston, Massachusetts, United States.ORCID 0000-0002-2435-7413 Funding
Imaging the Pulmonary Circulation to Aid Personalized Management of Acute Respiratory Distress SyndromeR01HL171199 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Maurizio Franco Cereda · 2024 to 2026
$2.4MImaging the Respiratory Effects of Truncal Adiposity in Acute Hypoxemic Respiratory FailureR01HL177025 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Lorenzo Berra, Maurizio Franco Cereda · 2025 to 2026
$1.4MHHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL171199HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL177025NHLBI NIH HHS R01 HL171199NHLBI NIH HHS R01 HL177025
6 · The paper itselfAbstract
Tidal changes in esophageal pressure (ΔPes) are used as a surrogate for pleural pressure changes (ΔPpl) to assess chest wall mechanics. The Baydur ratio evaluates pressure transmission and guides catheter positioning. The effects of correcting ΔPes using the Baydur ratio on the accuracy of ΔPpl estimation and its dependence on ventilation mode, spontaneous inspiratory effort, and body position remain unclear. In 10 pigs, ΔPpl was measured using intrapleural balloon catheters, whereas Pes was recorded at three esophageal locations in supine and prone positions. Animals underwent controlled and assisted ventilation. Baydur ratios were derived during assisted ventilation and from external chest compressions during controlled ventilation. ΔPes before and after correction was compared with ΔPpl using mixed-effects models and Bland-Altman analysis. In addition, we quantified the proportion of values with (ΔPes - ΔPpl) ≤ 1 cmH
Indexed as
EsophagusRespiratory MechanicsAnimalsPressureReproducibility of ResultsRespiration, ArtificialSwineBaydur testesophageal pressuremechanical ventilationpleural pressurerespiratory mechanics
Identifiers
PMID42412685
PMCPMC13421097
What OpenQuestion holds
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