Evidence map›Paper›PMID 42412267›Full record

ReviewJournal of echocardiography2026

Prognostic value of left atrial reservoir strain for major adverse cardiovascular events in coronary artery disease.

Thitiphan Srikulmontri, Phuuwadith Wattanachayakul, Suchanart Pantarote, Chanokporn Puchongmart, Pojsakorn Danpanichkul, Thanathip Suenghataiphorn, Danich Qadir, Sahil Banka, Aman Amanullah

Abstract readReview
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In one paragraph

Review in Journal of echocardiography, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thitiphan SrikulmontriDepartment of Internal Medicine, Jefferson Einstein Philadelphia Hospital, 5501 Old York Rd, Philadelphia, PA, 19141, USA. tys197@jefferson.edu.ORCID http://orcid.org/0009-0009-6672-649X
Phuuwadith WattanachayakulDepartment of Internal Medicine, Jefferson Einstein Philadelphia Hospital, 5501 Old York Rd, Philadelphia, PA, 19141, USA.
Suchanart PantarotePutthada Bangkhae Clinic, Bangkok, Thailand.
Chanokporn PuchongmartDepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, USA.
Pojsakorn DanpanichkulDepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, USA.
Thanathip SuenghataiphornDepartment of Internal Medicine, Griffin Hospital, Connecticut, USA.
Danich QadirDepartment of Internal Medicine, Jefferson Einstein Philadelphia Hospital, 5501 Old York Rd, Philadelphia, PA, 19141, USA.
Sahil BankaDepartment of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Aman AmanullahDepartment of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary artery disease (CAD) is associated with a high burden of long-term adverse cardiovascular events. Traditional risk stratification relies primarily on left ventricular ejection fraction, a measure limited to systolic function; however, myocardial ischemia affects both systolic and diastolic mechanics. Left atrial reservoir strain (LASr) is an integrated marker of left atrial-left ventricular function with potential prognostic relevance in CAD. We conducted a systematic review and meta-analysis of studies evaluating LASr in patients with CAD. PubMed and Embase were searched from inception through November 2, 2025. Hazard ratios (HRs) for major adverse cardiovascular events (MACE) were pooled using random-effects models, with prespecified subgroup analyses, meta-regression, sensitivity analyses, and publication bias analyses. Seventeen studies comprising 9,404 patients were included. Fifteen studies enrolled acute coronary syndrome (ACS) populations, whereas two enrolled chronic coronary syndrome/stable CAD populations. In the primary ACS analysis using adjusted HRs, higher LASr was significantly associated with a lower risk of MACE (pooled HR per 1% increase = 0.94; 95% CI, 0.92-0.95; I

Indexed as

Acute coronary syndromeEchocardiographyLeft atriumMagnetic resonance imagingMajor adverse cardiovascular eventsMyocardial strain

Identifiers

PMID42412267

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.