Evidence map›Paper›PMID 42412266›Full record

ArticleAging clinical and experimental research2026

Effects of vibroacoustic stimulation on hypertension: a pilot cross-over experimental study.

Sophie Saller, Francesca Fornasini, Italo Balzani, Filippo Ceccato, Federica Limongi, Leonardo Franz, Stefania Maggi, Leonardo Molinari, Marianna Noale, Nicola Bernardini and 2 more

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Article in Aging clinical and experimental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Sophie SallerDepartment of Medical Sciences, University of Ferrara, Ferrara, Italy. sophie.saller@edu.unife.it.
Francesca FornasiniAssociazione Italiana di Medicina Termale (AMIITTF), Bologna, Italy.
Italo BalzaniGeneral Medicine, Sant'Antonio Hospital, Padua, Italy.
Filippo CeccatoEndocrinology Unit, University of Padua, Padua, Italy.
Federica LimongiNational Research Council (CNR), Aging Branch - Institute of Neuroscience, Padua, Italy.
Leonardo FranzDepartment of Neurosciences, Otolaryngology Section, University of Padua, Padua, Italy.
Stefania MaggiNational Research Council (CNR), Aging Branch - Institute of Neuroscience, Padua, Italy.
Leonardo MolinariEmergency Medicine, Sant'Antonio Hospital, Padua, Italy.
Marianna NoaleNational Research Council (CNR), Aging Branch - Institute of Neuroscience, Padua, Italy.
Nicola BernardiniSanta Cecilia Conservatory of Music, Rome, Italy.
Caterina TrevisanDepartment of Medical Sciences, University of Ferrara, Ferrara, Italy.
Alois SallerGeneral Medicine, Sant'Antonio Hospital, Padua, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArterial hypertension is a frequent condition, affecting up to one-quarter of the global adult population. Both pharmacological and non-pharmacological treatments are recommended for hypertension management. Among the latter, recent studies have shown the positive effects of music therapy; however, evidence on the impact of vibroacoustic stimulation (VAS) is still limited.

objectiveThis pilot study aimed to explore the feasibility and effects of a VAS intervention on blood pressure (BP) and other cardiopulmonary and stress-related parameters in patients with hypertension.

methodsA pilot single-sequence cross-over experimental study was conducted on 11 male adults with mild to moderate hypertension. Patients underwent two sessions: on Day 1, they lay for 30 min without any vibratory or musical stimuli. On Day 2, they were placed on the vibroacoustic bed delivering 40 Hz vibration for 30 min, followed by 7 min of vibration combined with relaxing music. Physiological and stress-related parameters were measured at multiple time points during both sessions.

resultsPreliminary analysis showed no statistically significant differences between sessions. However, on Day 2, a more pronounced trend toward reductions in systolic and diastolic BP, heart and respiratory rate, and perceived stress was observed. A higher heart rate variability was recorded on Day 1 compared to Day 2.

conclusionThe VAS intervention appears feasible and may influence cardiovascular health parameters. Further studies with larger sample sizes are necessary to confirm these effects.

Indexed as

HypertensionVibrationAdultBlood PressureCross-Over StudiesHeart RateHumansMaleMiddle AgedMusic TherapyPilot ProjectsCross-over studiesHypertensionMusic therapyPilot projectsVibroacoustic stimulation

Identifiers

PMID42412266
PMCPMC13642424

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.