ArticleMicrobial genomics2026
Stabilizing features of cefotaximase harbouring plasmids enable persistence in UK livestock.
Article in Microbial genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Extended-spectrum cephalosporinases (ESCs) confer resistance to a range of beta-lactam compounds, including many cephalosporins and have grown in prevalence since the early 2000s. ESCs are often disseminated via plasmids, which can also encode other genes that confer bacterial fitness. Until recently, detailed characterization of plasmids encoding antimicrobial resistance genes was limited by the technical ability to close plasmid genomes. Recent advances in long-read technology have simplified this problem, facilitating the characterization of the genetic structure of plasmids and their component genes. This study examined the genetic mechanisms that underpin the stability of the most common cefotaximase-encoding plasmids in
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