Evidence map›Paper›PMID 42411191›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2026

DNA-Regulated Catalytic-Plasmonic Colocalization Enables Synergistic Signal Amplification in SERS and Nanozyme-Based Sensors.

Yeru Wang, Rongke Gao, Zihao Wang, Changbiao Zhan, Hancheng Liu, Wei Peng, Haiyang Wei, Long Li, Yiyue Yu, Wenbo Zhou and 3 more

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yeru WangState Key Laboratory of Chemical Safety, College of Control Science and Engineering, China University of Petroleum (East China), Qingdao, China.
Rongke GaoState Key Laboratory of Chemical Safety, College of Control Science and Engineering, China University of Petroleum (East China), Qingdao, China.ORCID https://orcid.org/0000-0001-9146-940X
Zihao WangState Key Laboratory of Chemical Safety, College of Control Science and Engineering, China University of Petroleum (East China), Qingdao, China.
Changbiao ZhanState Key Laboratory of Chemical Safety, College of Control Science and Engineering, China University of Petroleum (East China), Qingdao, China.
Hancheng LiuState Key Laboratory of Chemical Safety, College of Control Science and Engineering, China University of Petroleum (East China), Qingdao, China.
Wei PengState Key Laboratory of Chemical Safety, College of Control Science and Engineering, China University of Petroleum (East China), Qingdao, China.
Haiyang WeiState Key Laboratory of Chemical Safety, College of Control Science and Engineering, China University of Petroleum (East China), Qingdao, China.
Long LiState Key Laboratory of Chemical Safety, College of Control Science and Engineering, China University of Petroleum (East China), Qingdao, China.
Yiyue YuState Key Laboratory of Chemical Safety, College of Control Science and Engineering, China University of Petroleum (East China), Qingdao, China.
Wenbo ZhouState Key Laboratory of Chemical Safety, College of Control Science and Engineering, China University of Petroleum (East China), Qingdao, China.
Yujie FengDepartment of Hepatobiliary and Pancreatic Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.ORCID https://orcid.org/0000-0001-7999-1772
Yang LuState Key Laboratory of Chemical Safety, College of Control Science and Engineering, China University of Petroleum (East China), Qingdao, China.
Liandong YuState Key Laboratory of Chemical Safety, College of Control Science and Engineering, China University of Petroleum (East China), Qingdao, China.

Funding

Fundamental Research Funds for the Central Universities 26CX02023ANational Natural Science Foundation of China 52575648National Natural Science Foundation of China U22A20205Taishan Scholar Program of Shandong Province in China tsqnz20221124Taishan Scholar Program of Shandong Province in China tstp20230614
6 · The paper itself

Abstract

The critical need for accessible disease monitoring underscores the urgency of developing advanced point-of-care testing (POCT). We present a DNA-regulated catalytic-plasmonic colocalization-based synergy coupling mechanism that resolved the spatiotemporal disjunction commonly present in conventional SERS-catalysis systems through programmed spatial confinement. Rolling circle amplification-derived DNA nanocages were employed as programmable spatial regulators to precisely position Au@Pt nanozymes within plasmonic hotspots via base pair encoded hybridization, thereby enforcing spatial and temporal consistency between catalytic generation of Raman-active species and electromagnetic field enhancement. This strategy integrated coordinated interface, pore, and interlayer confinement, enabling cross-scale signal amplification from molecular to microscale levels. As a result, it yielded exceptional SERS enhancement (an approximate 41-fold versus controls), sensitivity (10

Indexed as

Biosensing TechniquesDNASpectrum Analysis, RamanCatalysisGoldMetal NanoparticlesPlatinumDNAGoldPlatinum3D flower‐shaped nanocagebimetallic nanozymeexosomenanocone array substrateportable dual‐modal device

Identifiers

PMID42411191
PMCPMC13486207

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.