ArticleJournal of gastric cancer2026
Clinical Outcomes and Prognostic Factors in Older Adult Patients Aged ≥75 Years With Early Gastric Cancer After Endoscopic Resections: A Nationwide Cohort Study.
Article in Journal of gastric cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeWith the aging population, the number of older adult patients undergoing endoscopic resections (ERs) for early gastric cancer (EGC) has increased. However, data on the long-term outcomes in these patients remain limited. We evaluated long- and short-term outcomes and identified factors associated with outcomes in older adult patients with EGC after ERs. MATERIALS AND
methodsData from older patients (aged ≥75 years) who underwent ERs for EGC between 2011 and 2019 were collected from the Korean National Health Insurance database. Baseline characteristics, clinical outcomes, and outcome-associated risk factors were investigated.
resultsIn total, 7,331 patients (mean age: 79.0 years) were included. During the 74.7-month median follow-up, 2,436 (33.2%) patients died, of whom 291 (4.0%) died of gastric cancer. The 3-, 5-, and 10-year overall survival rates were 91.3%, 82.1%, and 53.3%, respectively. The 3-, 5-, and 10-year cancer-specific survival rates were 98.3%, 96.9%, and 94.0%, respectively. Within 90 days after ER, 1,900 (25.9%) patients were readmitted, and 32 (0.4%) died. Risk factors associated with all-cause mortality were age ≥80 years, lower baseline hemoglobin level, higher baseline creatinine level, being underweight, current smoking, and a medical history of myocardial infarction, congestive heart failure, dementia, or renal disease. A body mass index ≥25 kg/m² was associated with lower overall mortality.
conclusionsWhen deciding on ER for EGC in late-older adult patients (aged ≥75 years), incorporating risk factors may be useful for risk stratification and prognostic counseling.
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