Observational studyEuropean journal of pain (London, England)2026
Sleep-Wake Disturbances in Patients With Chronic Pain-Associations With Physical Activity Levels.
Observational study in European journal of pain (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04649281 (Insomnia and Sleep Disturbances in Chronic Pain Patients - Relation to Physical Activity Level and Opioid Use), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Insomnia and Sleep Disturbances in Chronic Pain Patients - Relation to Physical Activity Level and Opioid Use
Who cites it
1 citing paper in PubMed.
- Sleep-Wake Disturbances in Patients With Chronic Pain-Associations With Physical Activity Levels.European journal of pain (London, England) · 2026Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundSleep-wake disturbances are frequently reported by patients with chronic pain. Physical activity, recommended as a first-line treatment for chronic pain, can be difficult to implement due to pain severity. This study aimed to assess the prevalence of insomnia and other sleep-wake disturbances in a cohort of patients with chronic pain and to explore the influence of physical activity, opioid use, reported pain, and symptoms of depression and anxiety.
methodsThis clinical cross-sectional study included 100 patients with chronic pain attending a specialist-level pain clinic. Participants were consecutively enrolled, and sleep and physical activity were evaluated using accelerometers. Additional assessments included the Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), symptoms of restless legs syndrome (RLS), STOP-Bang score, pain intensity assessed by Numeric Rating Scale (NRS), Hospital Anxiety and Depression Scale (HADS), and self-reported level of physical activity.
resultsOverall, nearly all participants experienced sleep-wake disturbances. Average sleep duration (hh:mm) was 5:30 (range, 1:46-9:52), and sleep efficiency was 64% (range, 28-81). Based on PSQI scores, 95% were classified as having poor sleep quality. Clinical insomnia (ISI ≥ 15p) was reported by 67%. A statistically significant correlation (r
conclusionsA wide range of sleep-wake disturbances were present in the examined cohort, highlighting the possible benefit of assessing sleep to optimise pain rehabilitation. SIGNIFICANCE STATEMENT: In this cohort, nearly all patients with chronic pain experienced sleep-wake disturbances, and none reached 85% sleep efficiency indicating stable sleep. These findings emphasise the need for a comprehensive assessment of sleep problems to improve the understanding and management of severe pain.
trial registrationClinicalTrials.gov: NCT04649281.
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