ArticleMedicine2026
A best evidence summary of anticoagulation management for extracorporeal membrane oxygenation in adults.
Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aims to synthesize the highest quality evidence for the anticoagulation management of extracorporeal membrane oxygenation (ECMO) in adults, providing an evidence-based foundation for clinical practice in ECMO anticoagulation.
methodsAn evidence summary approach was employed, adhering to the evidence summary reporting standards established by the Evidence-Based Nursing Center of Fudan University. Utilizing the "6S" evidence hierarchy model, comprehensive searches were conducted across both domestic and international databases for evidence pertaining to anticoagulation in ECMO patients. The literature types encompassed guidelines, expert consensus statements, best practices, and systematic reviews. The search period extended from January 1, 2019, to May 31, 2024. Two evidence-based reviewers independently extracted and synthesized relevant data from qualifying literature.
resultsThe initial search yielded 553 articles, from which 10 were selected following rigorous screening. These comprised 3 clinical guidelines, 3 clinical decisions, 2 systematic reviews, and 2 expert consensus articles. In total, 30 best evidence statements were distilled, categorized into pre-anticoagulation evaluation, individualized anticoagulation strategies, complication prevention and treatment, and nursing care. Among these, 25 were strong recommendations, 5 were weak recommendations, and 14 were secondary evidence.
conclusionThe study identified 30 best evidence statements for anticoagulation management in adult ECMO. Given the diverse origins of these evidence statements, clinical practitioners must consider contextual factors such as specific clinical settings and patient conditions prior to application. Future research should focus on the clinical application of this evidence summary to foster evidence implementation and to develop standardized clinical nursing protocols.
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