ArticleJournal of cardiovascular imaging2026
Echocardiographic changes following dual-chamber pacemaker implantation at a Malaysian tertiary heart center.
Article in Journal of cardiovascular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDual-chamber pacemaker implantation restores atrioventricular synchrony, but it might be associated with alterations in ventricular mechanics and valvular function. The echocardiographic effects of dual-chamber pacing in contemporary practice remain incompletely characterized.
methodsWe conducted a retrospective single-center study of patients who underwent dual-chamber pacemaker implantation and had transthoracic echocardiography performed before and after implantation in 2022. Changes in left ventricular ejection fraction (LVEF), ventricular and atrial functional parameters, strain-derived measures, and tricuspid regurgitation (TR) severity were assessed using paired statistical analyses.
resultsIn total, 57 patients were included. The mean LVEF declined from 59.6% before implantation to 55.8% after implantation (mean change, - 3.76%; 95% confidence interval [CI], - 7.45 to 0.08; P = 0.051). Among the strain-based measures, right ventricular global longitudinal strain (RVGLS) worsened by a mean of 3.10% (95% CI, 0.73 to 5.48; P = 0.012), and left atrial conduit strain (LAScd) declined by 3.74% (95% CI, 3.11 to 4.37; P = 0.032) following pacemaker implantation. Stuart-Maxwell testing showed no significant overall shift in TR severity following pacemaker implantation (χ
conclusionsDual-chamber pacemaker implantation was associated with early deterioration in myocardial deformation, particularly RVGLS and LAScd, despite preserved conventional systolic parameters. These functional changes were not accompanied by structural remodeling and were independent of TR progression, supporting a mechanism related to pacing-induced dyssynchrony and altered ventricular-atrial coupling. Strain imaging could offer incremental value in detecting early subclinical dysfunction in this population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.