Evidence map›Paper›PMID 42410551›Full record

ArticleBMC pregnancy and childbirth2026

Preoperative risk score for invasive uterus-sparing hemostasis at cesarean delivery: a retrospective cohort study.

Ying Chen, Zishu Zhan, Sheng Wan, Yan Wang, Meiqi Chai, Shengyi Gu, Cunjie Lin, Xiaolin Hua, Jing Peng

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Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

9 authors.

Ying Chen *The International Peace Maternity and Child Health Hospital, Shanghai Key Laboratory of Embryo Original Disease, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Zishu Zhan *Department of Biostatistics, Southern Medical University, Guangzhou, China.
Sheng Wan *The International Peace Maternity and Child Health Hospital, Shanghai Key Laboratory of Embryo Original Disease, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Yan WangDepartment of Obstetrics and Gynecology, Hainan Branch, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Sanya, China.
Meiqi ChaiDepartment of Obstetrics and Gynecology, Hainan Branch, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Sanya, China.
Shengyi GuThe International Peace Maternity and Child Health Hospital, Shanghai Key Laboratory of Embryo Original Disease, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Cunjie LinCenter for Applied Statistics and School of Statistics, Renmin University of China, Beijing, China. lincunjie@ruc.edu.cn.
Xiaolin HuaThe International Peace Maternity and Child Health Hospital, Shanghai Key Laboratory of Embryo Original Disease, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. huaxiaolin_sh@163.com.
Jing PengThe International Peace Maternity and Child Health Hospital, Shanghai Key Laboratory of Embryo Original Disease, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. penxiaoduo0725@163.com.

Funding

Joint Program on Health Science & Technology Innovation of Hainan Province WSJK2024QN003National Natural Science Foundation of China 82401996Shanghai Key Laboratory of Embryo Original Diseases Shelab202502Transformation Project of the Medical-Engineering Interdisciplinary Research Fund of Shanghai Jiao Tong University YG2026LC05
6 · The paper itself

Abstract

backgroundTo develop a simple preoperative risk score identifying women requiring invasive hemostatic interventions during cesarean delivery.

methodsThis retrospective cohort included women undergoing cesarean delivery at a Hainan maternity hospital. The primary outcome was intraoperative use of intrauterine balloon tamponade and/or uterine artery ligation. Continuous variables were compared using Student's t test or Mann-Whitney U test, and categorical variables using chi-square or Fisher's exact test. Multivariable logistic regression identified independent risk factors, which were translated into an integer-based risk score. Model performance was assessed using discrimination and calibration metrics. Women were classified into three risk categories. For each risk group, mean scores were calculated and radar-chart personas was created.

resultsAmong 8,687 cesarean deliveries, 386 (4.44%) required invasive hemostatic interventions. These women had greater blood loss, larger hemoglobin declines, higher transfusion rates, and more frequent peripartum hysterectomy. Independent predictors included placenta previa, low-lying placenta, severe preoperative anemia, prior postpartum hemorrhage, multiple gestation, preeclampsia, large leiomyoma, chorioamnionitis, and low platelet count. Based on these factors, we derived a preoperative risk score demonstrated good discrimination (AUC 0.7642, 95% CI: 0.7430-0.8305). The estimated probability of invasive hemostasis increased from about 2% in the low-risk group to (2.80 ~ 5.84)% in the medium-risk group and approximately 8% in the high-risk group. Although comprising only 8.28% of the cohort, the high-risk group accounted for 44% of all procedures.

conclusionsA simple preoperative risk score using routinely available variables can stratify the likelihood of invasive uterus-sparing hemostatic interventions during cesarean delivery and may help optimize perioperative preparedness.

Indexed as

Cesarean SectionHemostasis, SurgicalOrgan Sparing TreatmentsPostpartum HemorrhageUterine Balloon TamponadeAdultBlood Loss, SurgicalFemaleHumansPregnancyRetrospective StudiesRisk AssessmentRisk FactorsUterine ArteryUterusCesarean deliveryInvasive hemostatic interventionsPostpartum hemorrhagePreoperative risk stratificationRisk score

Identifiers

PMID42410551
PMCPMC13617848

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.