Evidence map›Paper›PMID 42410478›Full record

Observational studyReproductive health2026

Menstrual health and health-related quality of life in Spain: a multicenter cross-sectional study.

Andrea García-Egea, Tomàs López-Jiménez, Carmen Rodríguez-Domínguez, Vinita Mahtani-Chugani, Uxune Apalategi-Gómez, Maria José Fernández-Domínguez, Cristina Martínez-Bueno, Sara Domínguez-Salas, Casandra Del Pilar González-Hernández, Maialen Berridi-Agirre and 15 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Reproductive health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Andrea García-EgeaFundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Gran Via de les Corts Catalanes 587 attic, Barcelona, 08007, Spain.
Tomàs López-JiménezFundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Gran Via de les Corts Catalanes 587 attic, Barcelona, 08007, Spain.
Carmen Rodríguez-DomínguezDepartamento de Psicología Social, Evolutiva y de la Educación, Universidad de Huelva, Huelva, Spain.
Vinita Mahtani-ChuganiNetwork for Research on Chronicity, Primary Care and Health Promotion (RICAPPS), Madrid, Spain.
Uxune Apalategi-GómezNetwork for Research on Chronicity, Primary Care and Health Promotion (RICAPPS), Madrid, Spain.
Maria José Fernández-DomínguezNetwork for Research on Chronicity, Primary Care and Health Promotion (RICAPPS), Madrid, Spain.
Cristina Martínez-BuenoGrupo de Investigación en Salut Sexual y Reproductiva (GRASSIR), Barcelona, Spain.
Sara Domínguez-SalasDepartamento de Psicología Experimental, Universidad de Sevilla, Sevilla, Spain.
Casandra Del Pilar González-HernándezGerencia de Atención Primaria de Tenerife, Servicio Canario de Salud, Santa Cruz de Tenerife, Spain.
Maialen Berridi-AgirreOsakidetza-Servicio Vasco de Salud, Subdirección de Asistencia Sanitaria, Unidad Docente Multiprofesional de Atención Familiar y Comunitaria de Gipuzkoa, Donostia- San Sebastián, Spain.
Macarena Chacón-DocampoNetwork for Research on Chronicity, Primary Care and Health Promotion (RICAPPS), Madrid, Spain.
Jordi Baroja-BenlliureL'Associació de Drets Sexuals i Reproductius, Barcelona, Spain.
Ana Isabel Arcos-RomeroDepartamento de Psicología, Universidad Loyola Andalucía, Dos Hermanas, Seville, Spain.
María José González-LuisGerencia de Atención Primaria de Tenerife, Servicio Canario de Salud, Santa Cruz de Tenerife, Spain.
Estíbaliz Gamboa-MorenoNetwork for Research on Chronicity, Primary Care and Health Promotion (RICAPPS), Madrid, Spain.
Noemí López-ReyNetwork for Research on Chronicity, Primary Care and Health Promotion (RICAPPS), Madrid, Spain.
Carme Valls-LlobetCentro de Análisis y Programas Sanitarios (CAPS), Barcelona, Spain.
Irene Gómez-GómezDepartamento de Psicología Experimental, Universidad de Sevilla, Sevilla, Spain.
Celsa Perdiz-ÁlvarezÁrea sanitaria de Ourense, Verin e Barco Valdeorras, Ourense, Spain.
Mª Mercedes Vicente-HernándezGrupo de Investigación en Salut Sexual y Reproductiva (GRASSIR), Barcelona, Spain.
Alberto Armijo-SánchezDepartamento de Obstetricia y Ginecología, Hospital Universitario de Valme, Sevilla, Spain.
Rosa Ostos-SernaDepartamento de Obstetricia y Ginecología, Hospital Universitario de Valme, Sevilla, Spain.
Emma MotricoDepartamento de Psicología Evolutiva y de la Educación. Instituto de Biomedicina de Sevilla (IBIS) , Universidad de Sevilla, Sevilla, Spain.
Anna BerengueraFundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Gran Via de les Corts Catalanes 587 attic, Barcelona, 08007, Spain.
Laura Medina-PeruchaFundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Gran Via de les Corts Catalanes 587 attic, Barcelona, 08007, Spain. lmedina@idiapjgol.org.ORCID http://orcid.org/0000-0002-2981-2614

Funding

Instituto de Salud Carlos III PI22/01389
6 · The paper itself

Abstract

introductionMenstrual health plays a crucial role in health-related quality of life (HRQoL). However, there is a gap addressing HRQoL in relation to broader aspects of menstrual health definition. This study aims to analyse the relationship between menstrual health and self-reported health-related quality of life in women and people who menstruate (PWM) ≥ 18 years in five regions of Spain (Andalusia, Basque Country, Canary Islands, Catalonia, and Galicia).

methodsA cross-sectional survey-based study with gender perspective was conducted. Thirty-two healthcare centres took part in the study across five regions of Spain between May and September 2023. Participants were women and PWM aged 18 or over with at least one menstruation in the last 6 months. Self-reported sociodemographic, menstrual health and HRQoL variables (using EQ-5D-5 L scale) were collected. Descriptive statistics and linear regression models were performed. EQ-VAS scale was employed to perform sensitivity analyses.

resultsA total of 1,381 women and PWM were included (Mean age = 34.63, SD = 10.06). The mean of EQ-5D-5 L index was 0.88 (SD = 0.13) and EQ-VAS was 73.63 (SD = 22.60). Several menstrual health variables were significantly associated with lower HRQoL. The strongest associations were observed for high frequency of premenstrual symptoms (β= -0.144; 95%CI= -0.139 to -0.090), high impact of premenstrual symptoms (β= -0.071; 95%CI= -0.102 to -0.040), high impact on social participation during menstruation (β= -0.104; 95%CI= -0.128 to -0.080), moderate frequency of menstrual poverty (β= -0.054; 95%CI= -0.078 to -0.029) and menstrual pain intensity (β= -0.047; 95%CI= -0.068 to -0.025).

conclusionsThese findings highlight the substantial impact of menstrual health on HRQoL, particularly in some EQ-5D-5 L domains (usual activities, anxiety/depression, and pain/discomfort). From a public health perspective, it is important to recognise menstrual health as a relevant component of overall well-being of women and PWM. Specifically paying greater attention to menstrual health relation to general pain, emotional health and participation in daily activities when designing health promotion and primary healthcare interventions.

Indexed as

Health StatusMenstruationQuality of LifeAdolescentAdultCross-Sectional StudiesFemaleHumansMiddle AgedSpainSurveys and QuestionnairesYoung AdultCross-Sectional StudiesHealth InequitiesHealth-Related Quality of LifeMenstrual HealthMenstruationSocial Determinants of HealthWomen’s Health

Identifiers

PMID42410478
PMCPMC13621470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.