Evidence map›Paper›PMID 42410461›Full record

ReviewThe New phytologist2026

Cryptochrome-mediated signaling in root development.

Melina Pérez Torres, Ullas V Pedmale

Abstract readReview
In one paragraph

Review in The New phytologist, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Melina Pérez TorresCold Spring Harbor Laboratory, Cold Spring Harbor, NY, 11724, USA.ORCID https://orcid.org/0000-0002-9963-258X
Ullas V PedmaleCold Spring Harbor Laboratory, Cold Spring Harbor, NY, 11724, USA.ORCID https://orcid.org/0000-0002-3941-4468

Funding

The Role of Cryptochromes in environmental regulation of growthR35GM125003 · NIGMS · COLD SPRING HARBOR LABORATORY · PI Vincent U Pedmale · 2017 to 2026
$4.3M
National Science Foundation IOS-1755355NIGMS NIH HHS R35 GM125003NIGMS NIH HHS R35GM125003
6 · The paper itself

Abstract

Cryptochromes (CRYs) are evolutionarily conserved UV-A/blue-light photoreceptors that have functionally diversified across kingdoms, acting as photomorphogenic and flowering time regulators in plants, repressors of circadian clock in mammals, and as light-dependent circadian clock regulators in insects. In plants, photoactivated CRYs oligomerize to form phase-separated nuclear condensates to drive light-dependent transcription to affect growth and developmental programs. While CRY function in aboveground shoots is well-defined, recent studies implicate them as regulators of root development. Through both long-distance signaling and local activity in root tissues, CRYs influence auxin-mediated root growth, long-distance sucrose signaling, and cell division under distinct environmental conditions. Here, we review systemic and root-autonomous CRY-mediated pathways, environmental modulation, cross-species conservation, and discuss outstanding questions in CRY-regulated root growth.

Indexed as

CryptochromesPlant RootsSignal TransductionBlue LightCryptochromesblue‐light signalingcryptochromephotomorphogenesisphotoreceptorsroot developmentshoot‐to‐root signalingthermomorphogenesis

Identifiers

PMID42410461
PMCPMC13442984

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.