Evidence map›Paper›PMID 42410418›Full record

ArticleBMC surgery2026

Safety and oncologic efficacy of robotic surgery compared to open surgery after neoadjuvant therapy for pancreatic cancer.

Pengyu Li, Hui Zhang, Juan Li, Peng Zhang, Qiang Xu, Wenjing Liu, Haomin Chen, Weijie Chen, Mingfei Wang, Yuqian Kan and 5 more

Abstract readComparative Study
In one paragraph

Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Pengyu Li *Department of General Surgery, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College and Chinese Academy of Medical Sciences, No. 1, Shuai Fu Yuan, Dongcheng District, Beijing, 100730, China.
Hui Zhang *Department of Pathology, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Juan Li *Department of Radiology, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Peng ZhangDepartment of Radiology, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Qiang XuDepartment of General Surgery, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College and Chinese Academy of Medical Sciences, No. 1, Shuai Fu Yuan, Dongcheng District, Beijing, 100730, China.
Wenjing LiuDepartment of General Surgery, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College and Chinese Academy of Medical Sciences, No. 1, Shuai Fu Yuan, Dongcheng District, Beijing, 100730, China.
Haomin ChenDepartment of General Surgery, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College and Chinese Academy of Medical Sciences, No. 1, Shuai Fu Yuan, Dongcheng District, Beijing, 100730, China.
Weijie ChenDepartment of General Surgery, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College and Chinese Academy of Medical Sciences, No. 1, Shuai Fu Yuan, Dongcheng District, Beijing, 100730, China.
Mingfei WangDepartment of General Surgery, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College and Chinese Academy of Medical Sciences, No. 1, Shuai Fu Yuan, Dongcheng District, Beijing, 100730, China.
Yuqian KanDepartment of General Surgery, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College and Chinese Academy of Medical Sciences, No. 1, Shuai Fu Yuan, Dongcheng District, Beijing, 100730, China.
Xinwei CuiDepartment of General Surgery, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College and Chinese Academy of Medical Sciences, No. 1, Shuai Fu Yuan, Dongcheng District, Beijing, 100730, China.
Yaqi WangDepartment of General Surgery, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College and Chinese Academy of Medical Sciences, No. 1, Shuai Fu Yuan, Dongcheng District, Beijing, 100730, China.
Huadan XueDepartment of Radiology, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Zhiyong LiangDepartment of Pathology, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Menghua DaiDepartment of General Surgery, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College and Chinese Academy of Medical Sciences, No. 1, Shuai Fu Yuan, Dongcheng District, Beijing, 100730, China. daimh@pumch.cn.

Funding

CAMS Innovation Fund for Medical Sciences (CIFMS) 2024-I2M-ZD-001the National High Level Hospital Clinical Research Funding 2022-PUMCH-B-004the project of National Natural Science Foundation of China 82573271
6 · The paper itself

Abstract

backgroundNeoadjuvant therapy (NAT) has become the recommended treatment approach for patients with borderline resectable or locally advanced pancreatic cancer. However, pancreatic peritumoral fibrosis and proximity of the tumor to major vessels make surgery after NAT challenging. The feasibility and safety of robotic approaches remain unclear.

methodsA retrospective analysis was conducted on consecutive pancreatic cancer patients who underwent either open pancreatic surgeries (OPS) or robotic pancreatic surgeries (RPS) following NAT between February 2017 and April 2025. Outcomes, including R0 resection rates, postoperative complication rates, disease-free survival (DFS), and overall survival (OS), were compared between the two groups.

resultsThe rate of combined vascular resection and reconstruction was significantly higher in OPS group compared to RPS group following NAT. A total of 43 patients underwent surgical resection which did not require venous segmental resection and reconstruction, including 23 RPS and 20 OPS, were finally included in the analysis. The two groups were well balanced in baseline characteristics, except for BMI. In the RPS group, one case (4.3%) was converted into laparotomy. The RPS group was associated with longer operative time (340.0 min vs. 254.0 min, p = 0.015). The number of harvested lymph nodes was significantly higher in the RPS group compared to the OPS group(25 vs. 18, p = 0.049). There were no significant differences in R0 resection rates between the groups. The overall complication rate was significantly lower in the RPS group (21.7% vs. 55.0%, p = 0.024), while the rates of severe complications, clinically relevant pancreatic fistula, and postoperative hemorrhage did not differ between groups. Postoperative hospital stay was slightly shorter in the RPS group, though not statistically significant. There were no significant differences in DFS or OS.

conclusionIn carefully selected patients with pancreatic cancer following neoadjuvant therapy who did not require vascular segmental resection and reconstruction, a robotic approach appeared technically feasible and was associated with favorable short-term postoperative outcomes and a greater lymph node yield. These findings should be considered exploratory, and further prospective studies are warranted to better define the role of robotic surgery in this setting.

Indexed as

Neoadjuvant TherapyPancreatectomyPancreatic NeoplasmsRobotic Surgical ProceduresAgedFeasibility StudiesFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesTreatment OutcomeNeoadjuvant therapyOpen surgeryPancreatic cancerRobotic surgery

Identifiers

PMID42410418
PMCPMC13617835

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