Evidence map›Paper›PMID 42410412›Full record

ArticleInternational journal of mental health systems2026

Bridging clinical needs and economic barriers: a national survey of antidepressant prescribing across 25 hospitals in Thailand.

Pornjira Pariwatcharakul, Krittisak Anuroj, Nopporn Tantirangsee, Keerati Pattanaseri, Chonnakarn Jatchavala, Nitchawan Kerdcharoen, Papan Thaipisuttikul, Kanthee Anantapong, Lampu Kosulwit, Nuth Graipaspong and 36 more

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Article in International journal of mental health systems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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46 authors.

Pornjira PariwatcharakulDepartment of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Krittisak AnurojDepartment of Psychiatry, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok, Thailand.
Nopporn TantirangseeBureau of Mental Health Service Administration, Department of Mental Health, Ministry of Public Health, Nonthaburi, Thailand.
Keerati PattanaseriDepartment of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. keerati.pat@mahidol.ac.th.
Chonnakarn JatchavalaDepartment of Psychiatry, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
Nitchawan KerdcharoenDepartment of Psychiatry, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.
Papan ThaipisuttikulDepartment of Psychiatry, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Kanthee AnantapongDepartment of Psychiatry, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
Lampu KosulwitDepartment of Psychiatry, Faculty of Medicine, Thammasat University, PathumThani, Thailand.
Nuth GraipaspongGalya Rajanagarindra Institute, Bangkok, Thailand.
Pavarud PuangsriSchool of Medicine, Walailak University, Nakhon Si Thammarat, Thailand.
Poom ChompoosriSchool of Medicine, Mae Fah Luang University, Chiang Rai, Thailand.
Tiyarat KayankitMinistry of Public Health, Buddhachinaraj Phitsanulok Hospital, Phitsanulok, Thailand.
Pavita ChongsuksiriMinistry of Public Health, Buddhachinaraj Phitsanulok Hospital, Phitsanulok, Thailand.
Sirina SatthapisitDepartment of Psychiatry, Khon Kaen Hospital, Khon Kaen, Thailand.
Songpon LodthanongDepartment of Psychiatry, Trakanphuetphon Hospital, Ubon Ratchathani, Thailand.
Amornrut BangphichetDepartment of Psychiatry and Addiction, Takuapa Hospital, Takua Pa, Phang Nga, Thailand.
Veevarin CharoenpornDepartment of Psychiatry, Faculty of Medicine, Thammasat University, PathumThani, Thailand.
Saratcha TiensuntisookFaculty of Medicine Ramathibodi Hospital, Chakri Naruebodindra Medical Institute, Mahidol University, Samutprakarn, Thailand.
Kamolvisa TechapoonponDepartment of Psychiatry, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.
Warut AunjitsakulDepartment of Psychiatry, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
Kantanut YutrirakDepartment of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Kritta SupanimitamornDepartment of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Tidarat PuranachaikereDepartment of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Apichat SaengsinManarom Hospital, Bangkok, Thailand.
Maneekwan RujirojsuwanPhitsanulok Psychiatric Hospital, Phitsanulok, Thailand.
Orapa KhemtongPhitsanulok Psychiatric Hospital, Phitsanulok, Thailand.
Panklow SiriarchawatanaPhitsanulok Psychiatric Hospital, Phitsanulok, Thailand.
Pawaris AsawalertsaengNakhonratchasima Rajanagarindra Psychiatric Hospital, Nakhonratchasima, Thailand.
Pawitra MongkolnaowaratGalya Rajanagarindra Institute, Bangkok, Thailand.
Pichapuk JarasrassameeSuanprung Psychiatric Hospital, Chiang Mai, Thailand.
Ploypan WangrotjanaratGalya Rajanagarindra Institute, Bangkok, Thailand.
Tattaporn SuksintaranonPhitsanulok Psychiatric Hospital, Phitsanulok, Thailand.
Warith MongkolnaowaratGalya Rajanagarindra Institute, Bangkok, Thailand.
Warot LamyaiNakhon Phanom Rajanagarindra Psychiatric Hospital, Nakhon Phanom, Thailand.
Wattanapong PansawatPrasrimahabhodi Psychiatric Hospital, Ubon Ratchathani, Thailand.
Witchuda ChantaratGalya Rajanagarindra Institute, Bangkok, Thailand.
Pavat AroonpetSa-Kaew Rajanagarindra Psychiatric Hospital, Sa-Kaew, Thailand.
Nutthaporn Jaisamut SakunphaetMental Health Center 11, Surat Thani, Thailand.
Naratip Sa-NguanpanichDepartment of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Lakkana ThongchotDepartment of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Dutsadee JuengsiragulwitBureau of Mental Health Service Administration, Department of Mental Health, Ministry of Public Health, Nonthaburi, Thailand.
Burin SuraaroonsamritDepartment of Mental Health, Ministry of Public Health, Bureau of Mental Health Academic Affairs, Nonthaburi, Thailand.
Shih-Ku LinDepartment of Psychiatry, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Takahiro A KatoDepartment of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Woraphat Ratta-AphaDepartment of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrescribing patterns are highly influenced by national healthcare structures. This study aimed to investigate the current antidepressant prescribing patterns, associated diagnoses, and the impact of financial barriers on clinical decision-making in Thailand.

methodsWe conducted a multicenter national survey on psychotropic drug prescribing across 25 Thai hospitals from December 2023 to March 2024. Utilizing the Research on East Asia Psychotropic Prescription Patterns (REAP-AD3) protocol for antidepressant data, we integrated country-specific modules assessing patient economic burden and physician preferences.

resultsData from 604 patients were analyzed. Selective serotonin reuptake inhibitors (SSRIs) were the most prescribed class (70.2%), followed by tricyclic antidepressants (TCAs) (13.9%) and serotonin antagonist and reuptake inhibitor (SARI) trazodone (12.7%). Most common antidepressant users' diagnoses were depressive disorders (55.0%), followed by substance use (15.2%) and psychotic disorders (13.7%). A substantial number of psychiatrists reported feeling restricted by financial and reimbursement limitations related to each prescription, specifically citing limited drug availability (21.9%, n = 131), the patient's reimbursement scheme (36.3%, n = 217), and the patient's financial status (33.9%, n = 203). In addition, 34.3% (n = 205) indicated that they wanted to change the current prescription if there were not any financial barriers, especially for patients currently on TCAs (49.4%, χ

conclusionSSRIs were the most commonly prescribed antidepressant in Thailand. However, financial constraints may have contributed to the use of TCAs against clinician preference. Policy revisions addressing both medication access and indirect costs are essential to allow psychiatrists to prescribe antidepressants according to clinical needs, which may sustainably optimize mental health outcomes in Thailand.

Indexed as

AntidepressantsEconomic burdenHealth policyPrescribing patternsREAP-AD3Thailand

Identifiers

PMID42410412
PMCPMC13621676

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