Evidence map›Paper›PMID 42410366›Full record

SynthesisBMC geriatrics2026

Intramedullary fixation versus arthroplasty in the treatment of geriatric trochanteric fractures: a systematic review and meta-analysis.

Zheng Liu, Frankie Ka Li Leung, Shuzhuang Peng

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zheng LiuDepartment of Plastic Surgery, the First Affiliated Hospital of Zhengzhou University, 1St Long Hu Zhong Huan Road, Zhengzhou, Henan, China. pilotliu@connect.hku.hk.
Frankie Ka Li LeungDepartment of Orthopaedics and Traumatology, School of Clinical Medicine, the University of Hong Kong, Hong Kong, China. klleunga@hku.hk.
Shuzhuang PengSchool of Biomedical Sciences, the University of Hong Kong, Hong Kong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTrochanteric fracture (TF) is of high incidence, especially among geriatric patients with osteoporosis. It imposes a heavy burden on both society and individuals. Surgical operation is the preferred choice for the treatment of TF, and intramedullary fixation and arthroplasty are two mainstream surgical procedures performed in clinical settings. This meta-analysis aims to attempt to explore the superiority of intramedullary fixation and arthroplasty in treating geriatric TF concerning the functional recovery, complications, mortality, and other operative details.

methodsThis review was planned, conducted, and reported following the PRISMA 2020 guidelines. By searching online databases (PubMed, Cochrane Library, Web of Science), related prospective studies from the year of 2000 to April 2024 were included in this meta-analysis. The language was restricted to English and Chinese. Studies were screened by two researchers independently, and the results of interest were analyzed by RevMan (version 5.4) and R (version 4.5.3). Both the conventional DerSimonian-Laird (DL) method and the Hartung-Knapp-Sidik-Jonkman (HKSJ) adjustment were employed to compare results, enhancing methodological transparency, and ensuring a more objective interpretation of therapeutic differences.

resultsA total of 981 studies were screened, of which 12 studies (7 randomized controlled trials (RCTs) and 5 prospective non-randomized controlled trials (non-RCTs)) involving 1,262 patients were finally included. Intramedullary fixation was associated with significantly shorter operative time (WMD -21.47, 95% CI -36.84 to -6.11, P = 0.006), reduced operative blood loss (WMD -176.29, 95% CI -232.32 to -120.27, P < 0.001), and superior long-term functional recovery at 12 months (SMD 0.50, 95% CI 0.16 to 0.84, P = 0.004). Notably, while initial DL estimates suggested that arthroplasty had advantages in short-term functional recovery (within 6 months, P = 0.04) and lower implant-related complications (P = 0.003), these differences lost statistical significance following the more conservative HKSJ adjustment (P = 0.1069 and P = 0.0565, respectively). However, arthroplasty maintained a lower revision rate (P = 0.009) across both models. Subgroup analyses indicated that nail types and fracture stability did not fundamentally alter the comparative trends (P

conclusionsIntramedullary fixation remains the primary choice for geriatric trochanteric fractures due to shorter operative times, reduced blood loss, and superior long-term function. Arthroplasty may offer potential advantages in short-term recovery, lower revision rates, and fewer implant-related complications, though these benefits were sensitive to the statistical model used. Therefore, primary arthroplasty should be considered a strategic alternative rather than a routine replacement, particularly for patients with poor bone quality or pre-existing hip arthritis.

Indexed as

Arthroplasty, Replacement, HipFracture Fixation, IntramedullaryHip FracturesAgedHumansProximal Femoral FracturesTreatment OutcomeArthroplastyIntramedullary fixationMeta-analysisTrochanteric fracture

Identifiers

PMID42410366
PMCPMC13625458

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.