Evidence map›Paper›PMID 42410284›Full record

ArticleMolecular neurobiology2026

Curcumin Attenuates Cuproptosis via Activating Autophagy Through Inhibition of the AKT/mTOR/P70S6K-Signaling Pathway in Parkinson's Disease Models.

Feng Ren, Yanpeng Sun, Man Wang, Kun Zheng, Chao Zuo, Hui Shang, Jing Zhu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular neurobiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Feng Ren *Taihe Hospital, Affiliated Hubei University of Medicine, Shiyan, Hubei, China.
Yanpeng Sun *Taihe Hospital, Affiliated Hubei University of Medicine, Shiyan, Hubei, China.
Man WangTaihe Hospital, Affiliated Hubei University of Medicine, Shiyan, Hubei, China.
Kun ZhengTaihe Hospital, Affiliated Hubei University of Medicine, Shiyan, Hubei, China.
Chao ZuoTaihe Hospital, Affiliated Hubei University of Medicine, Shiyan, Hubei, China.
Hui ShangTaihe Hospital, Affiliated Hubei University of Medicine, Shiyan, Hubei, China. huishang2025@163.com.
Jing ZhuTaihe Hospital, Affiliated Hubei University of Medicine, Shiyan, Hubei, China. jing_zhu0719@163.com.ORCID https://orcid.org/0000-0002-2860-3685

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This research surveyed the therapeutic potential of curcumin (Cur) in Parkinson's disease (PD), focusing on its effects on cuproptosis and underlying molecular mechanisms. A MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)-induced mouse model and a MPP

Indexed as

AutophagyCuproptosisCurcuminParkinson DiseaseProto-Oncogene Proteins c-aktRibosomal Protein S6 Kinases, 70-kDaSignal TransductionTOR Serine-Threonine KinasesAnimalsDisease Models, AnimalDopaminergic NeuronsMaleMiceNeuroprotective AgentsPC12 CellsRatsCurcuminNeuroprotective AgentsProto-Oncogene Proteins c-aktRibosomal Protein S6 Kinases, 70-kDaTOR Serine-Threonine KinasesAKT/mTOR/P70S6KAutophagyCuproptosisCurcuminParkinson’s disease

Identifiers

PMID42410284
PMCPMC13337753

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.