ArticleEuropean journal of pediatrics2026
The anatomical type of atresia drives the risk of home parenteral nutrition of infants with congenital jejunoileal atresia.
Article in European journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Congenital jejunoileal atresia is a rare intestinal malformation with favourable survival in high-income settings, but affected infants remain at risk of prolonged intestinal failure and dependence on parenteral nutrition (PN). Data on nutritional outcomes by anatomical subtype remain limited. We aimed to quantify the risk of discharge with home PN according to the type of congenital jejunoileal atresia and to compare neonatal outcomes across anatomical subtypes. We conducted a single-centre retrospective cohort study including infants with congenital jejunoileal atresia managed between 2013 and 2022. Atresia was classified according to the Grosfeld classification and grouped as simple (types I-IIIa), multiple (type IV), or apple-peel (type IIIb). Sixty-four children were included. The most common type of atresia was single (n = 42, 66%), followed by multiple (n = 13, 20%) and apple-peel atresia (n = 9, 14%). Two infants died during hospitalisation. Compared with simple atresia, multiple (OR [95% CI] = 20 [2.0 - 203]) and apple-peel atresia (OR [95% CI] = 32 [3.0 - 345]) were associated with a significantly increased risk of home PN. These associations remained robust after excluding syndromic cases. Cholestasis increased with anatomical severity.
conclusionAnatomical complexity is a major determinant of nutritional prognosis in congenital jejunoileal atresia. The type of atresia strongly predicts the risk of discharge with home PN, with a clear severity gradient from simple to multiple and apple-peel atresia. These findings support early parental counselling, optimized discharge planning and long-term follow-up strategies. WHAT IS KNOWN: • Congenital jejunoileal atresia has a good overall survival but is frequently complicated by intestinal failure requiring parenteral nutrition. • The influence of anatomical subtype on postoperative nutritional outcomes remains insufficiently characterized. WHAT IS NEW: • Apple-peel and multiple atresia are associated with a substantially higher risk of home parenteral nutrition at discharge compared with simple atresia. • There is a clear stepwise increase in nutritional risk according to anatomical complexity, making subtype a key prognostic factor.
Indexed as
Identifiers
42410137What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.