Evidence map›Paper›PMID 42410002›Full record

ReviewPathologie (Heidelberg, Germany)2026

[Hereditary cancer predisposition syndromes-significance of gynecological cancers].

Anne Kathrin Höhn, Annette Staebler, Felix K F Kommoss, Jutta Huvila, Julia Müller, Grit Gesine Ruth Hiller, Lars-Christian Horn

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Pathologie (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anne Kathrin HöhnInstitut für Pathologie, Abteilung Gynäkopathologie, Universitätsklinikum Leipzig, AöR, Leipzig, Deutschland. annekathrin.hoehn@medizin.uni-leipzig.de.
Annette StaeblerInstitut für Pathologie und Neuropathologie, Bereich Gynäkopathologie und Mammapathologie, Universität Tübingen, Tübingen, Deutschland.
Felix K F KommossPathologisches Institut, Sektion Gynäkologische Pathologie, Universitätsklinikum Heidelberg, Heidelberg, Deutschland.
Jutta HuvilaDepartment für Pathologie, Universität und Universitätskrankenhaus von Turku, Turku, Finnland.
Julia MüllerInstitut für Pathologie, Abteilung Gynäkopathologie, Universitätsklinikum Leipzig, AöR, Leipzig, Deutschland.
Grit Gesine Ruth HillerInstitut für Pathologie, Abteilung Gynäkopathologie, Universitätsklinikum Leipzig, AöR, Leipzig, Deutschland.
Lars-Christian HornInstitut für Pathologie, Abteilung Gynäkopathologie, Universitätsklinikum Leipzig, AöR, Leipzig, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A number of gynecologic cancers are associated with hereditary cancer syndromes (HCS). These neoplasms may represent the sentinel lesion for HCS within the affected individual/family. Many of these tumors exhibit distinctive histologic and immunohistochemical features that are associated with HCS tumors. By recognizing these features, pathologists may help in identifying HCS which is important regarding primary prevention efforts and personalized care for affected patients. This review summarizes morphologic features for HCS, such as BRCA, Lynch, Peutz-Jeghers, DICER1, rhabdoid tumor predisposition syndrome 2 (SMARCA4-deficiency), tuberous sclerosis, PTEN hamartoma tumor syndrome (Cowden), familiar adenomatous polyposis, and nevoid basal cell carcinoma syndrome.

Indexed as

Genetic Predisposition to DiseaseGenital Neoplasms, FemaleNeoplastic Syndromes, HereditaryColorectal Neoplasms, Hereditary NonpolyposisDEAD-box RNA HelicasesFemaleGerm-Line MutationHamartoma Syndrome, MultipleHumansPeutz-Jeghers SyndromeRibonuclease IIIDEAD-box RNA HelicasesDICER1 protein, humanRibonuclease IIIBRCAGerm-line mutationGynecologic tumorsLynch syndromePeutz-Jeghers syndrome

Identifiers

PMID42410002

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.