Evidence map›Paper›PMID 42409967›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Improving the quality of newborn screening dry blood spot specimens in the nursery.

Diksha Shrestha, Kelechi Ikeri, Vicki Curtis, Karen Williams, Victoria Humphries, Michael Zayek

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Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Diksha ShresthaDivision of Neonatology, University of South Alabama Children's and Women's Hospital, Mobile, AL, USA. dikshas@health.southalabama.edu.ORCID http://orcid.org/0009-0002-2574-4228
Kelechi IkeriDivision of Neonatology, University of South Alabama Children's and Women's Hospital, Mobile, AL, USA.ORCID http://orcid.org/0000-0002-1482-0320
Vicki CurtisDivision of Nursing, University of South Alabama Children's and Women's Hospital, Mobile, AL, USA.
Karen WilliamsDivision of Nursing, University of South Alabama Children's and Women's Hospital, Mobile, AL, USA.
Victoria HumphriesDivision of Nursing, University of South Alabama Children's and Women's Hospital, Mobile, AL, USA.
Michael ZayekDivision of Neonatology, University of South Alabama Children's and Women's Hospital, Mobile, AL, USA.ORCID http://orcid.org/0000-0002-2835-7023

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDefective newborn screening (NBS) specimens require repeat collection, potentially delaying care and increasing healthcare costs.

objectiveTo reduce unsatisfactory NBS rates in the well-baby nursery from 35% to <10% over 12-months through establishment of a dedicated specimen collection team.

methodsStaff education, establishment of a specimen collection team, and pre-dispatch review were implemented. Outcome measure was the unsatisfactory specimen rate. Process measure was the proportion of specimens collected by the specimen collection team. Balancing measure was the proportion of specimens obtained >48 h after birth.

resultsDuring the intervention period (n = 2395), unsatisfactory specimen rate decreased to 5.3% with special cause variation, exceeding our target, and was sustained for 18 months (n = 3668). The specimen collection team collected all specimens. Specimens obtained >48 h after birth decreased from 6.5% to 4.7%.

conclusionNBS specimen collection by trained staff with pre-dispatch review can improve specimen quality without impacting the timeliness of screening.

Identifiers

PMID42409967

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.